| 2021-10-22 | 83 - 115 | BOSTON CELTICS v. TORONTO RAPTORS | * | 30:20 | 18 | 8 / 14 | 6 / 10 | 2 / 4 | 0 / 1 | 6 | 0 | 4 | 0 | 2 | 5 | 3 | 24 |
| 2021-10-24 | 97 - 107 | BOSTON CELTICS @ HOUSTON ROCKETS | * | 36:55 | 31 | 12 / 24 | 8 / 13 | 4 / 11 | 3 / 4 | 9 | 0 | 2 | 1 | 1 | 1 | 4 | 30 |
| 2021-10-27 | 107 - 116 | BOSTON CELTICS v. WASHINGTON WIZARDS | * | 35:40 | 23 | 9 / 22 | 8 / 14 | 1 / 8 | 4 / 8 | 6 | 1 | 2 | 0 | 0 | 2 | 2 | 17 |
| 2021-11-01 | 114 - 128 | BOSTON CELTICS v. CHICAGO BULLS | * | 36:15 | 20 | 8 / 22 | 7 / 18 | 1 / 4 | 3 / 4 | 3 | 1 | 3 | 2 | 0 | 1 | 3 | 15 |
| 2021-11-03 | 79 - 92 | BOSTON CELTICS @ ORLANDO MAGIC | * | 33:55 | 14 | 4 / 16 | 3 / 10 | 1 / 6 | 5 / 8 | 6 | 0 | 3 | 1 | 2 | 2 | 1 | 9 |
| 2021-11-04 | 78 - 95 | BOSTON CELTICS @ MIAMI HEAT | * | 29:24 | 10 | 3 / 13 | 1 / 8 | 2 / 5 | 2 / 3 | 8 | 0 | 2 | 1 | 0 | 1 | 4 | 11 |
| 2021-11-06 | 107 - 104 | BOSTON CELTICS @ DALLAS MAVERICKS | * | 38:27 | 32 | 12 / 19 | 6 / 11 | 6 / 8 | 2 / 2 | 10 | 1 | 2 | 2 | 1 | 4 | 4 | 43 |
| 2021-11-10 | 104 - 88 | BOSTON CELTICS v. TORONTO RAPTORS | * | 36:33 | 22 | 8 / 24 | 5 / 17 | 3 / 7 | 3 / 4 | 10 | 1 | 7 | 1 | 0 | 2 | 3 | 26 |
| 2021-11-13 | 91 - 89 | BOSTON CELTICS @ CLEVELAND CAVALIERS | * | 35:22 | 21 | 8 / 22 | 7 / 14 | 1 / 8 | 4 / 5 | 4 | 0 | 2 | 0 | 0 | 6 | 1 | 18 |
| 2021-11-15 | 92 - 98 | BOSTON CELTICS @ CLEVELAND CAVALIERS | * | 35:40 | 23 | 7 / 20 | 5 / 12 | 2 / 8 | 7 / 7 | 7 | 1 | 5 | 1 | 2 | 2 | 2 | 24 |
| 2021-11-17 | 110 - 99 | BOSTON CELTICS @ ATLANTA HAWKS | * | 37:46 | 34 | 12 / 22 | 7 / 10 | 5 / 12 | 5 / 6 | 6 | 3 | 5 | 1 | 1 | 4 | 2 | 41 |
| 2021-11-19 | 130 - 108 | BOSTON CELTICS v. LOS ANGELES LAKERS | * | 33:31 | 37 | 13 / 26 | 9 / 17 | 4 / 9 | 7 / 7 | 10 | 1 | 2 | 3 | 1 | 1 | 3 | 40 |
| 2021-11-20 | 111 - 105 | BOSTON CELTICS v. OKLAHOMA CITY THUNDER | * | 33:46 | 33 | 11 / 22 | 5 / 10 | 6 / 12 | 5 / 7 | 8 | 0 | 5 | 0 | 1 | 1 | 2 | 33 |
| 2021-11-22 | 108 - 90 | BOSTON CELTICS v. HOUSTON ROCKETS | * | 33:42 | 30 | 10 / 22 | 9 / 13 | 1 / 9 | 9 / 9 | 6 | 0 | 3 | 1 | 0 | 1 | 3 | 29 |
| 2021-11-24 | 104 - 123 | BOSTON CELTICS v. BROOKLYN NETS | * | 30:19 | 15 | 4 / 16 | 3 / 7 | 1 / 9 | 6 / 8 | 4 | 4 | 3 | 1 | 1 | 5 | 2 | 17 |
| 2021-11-28 | 97 - 109 | BOSTON CELTICS @ TORONTO RAPTORS | * | 37:44 | 8 | 2 / 16 | 1 / 11 | 1 / 5 | 3 / 4 | 7 | 0 | 10 | 1 | 0 | 4 | 2 | 15 |
| 2021-12-01 | 88 - 87 | BOSTON CELTICS v. PHILADELPHIA 76ERS | * | 36:56 | 26 | 9 / 20 | 6 / 12 | 3 / 8 | 5 / 5 | 16 | 0 | 2 | 1 | 0 | 2 | 2 | 36 |
| 2021-12-03 | 137 - 130 | BOSTON CELTICS @ UTAH JAZZ | * | 38:09 | 37 | 12 / 25 | 10 / 14 | 2 / 11 | 11 / 11 | 5 | 1 | 5 | 0 | 1 | 0 | 1 | 34 |
| 2021-12-04 | 117 - 145 | BOSTON CELTICS @ PORTLAND TRAIL BLAZERS | * | 30:51 | 31 | 9 / 17 | 5 / 11 | 4 / 6 | 9 / 10 | 10 | 0 | 4 | 0 | 0 | 2 | 1 | 38 |
| 2021-12-07 | 117 - 102 | BOSTON CELTICS @ LOS ANGELES LAKERS | * | 33:58 | 34 | 13 / 22 | 8 / 15 | 5 / 7 | 3 / 5 | 6 | 2 | 3 | 1 | 1 | 5 | 2 | 39 |
| 2021-12-08 | 114 - 111 | BOSTON CELTICS @ LOS ANGELES CLIPPERS | * | 36:28 | 29 | 9 / 20 | 7 / 13 | 2 / 7 | 9 / 10 | 9 | 1 | 2 | 2 | 1 | 6 | 4 | 36 |
| 2021-12-10 | 111 - 90 | BOSTON CELTICS @ PHOENIX SUNS | * | 33:35 | 24 | 10 / 25 | 9 / 18 | 1 / 7 | 3 / 6 | 5 | 2 | 3 | 0 | 1 | 4 | 2 | 19 |
| 2021-12-13 | 117 - 103 | BOSTON CELTICS v. MILWAUKEE BUCKS | * | 38:04 | 42 | 16 / 25 | 9 / 12 | 7 / 13 | 3 / 5 | 4 | 1 | 4 | 3 | 0 | 3 | 1 | 46 |
| 2021-12-18 | 114 - 107 | BOSTON CELTICS v. NEW YORK KNICKS | * | 36:27 | 25 | 9 / 24 | 6 / 11 | 3 / 13 | 4 / 4 | 7 | 2 | 2 | 0 | 0 | 3 | 4 | 24 |
| 2021-12-20 | 103 - 108 | BOSTON CELTICS v. PHILADELPHIA 76ERS | * | 38:54 | 17 | 5 / 14 | 5 / 11 | 0 / 3 | 7 / 9 | 8 | 1 | 6 | 2 | 2 | 6 | 3 | 27 |
| 2021-12-22 | 111 - 101 | BOSTON CELTICS v. CLEVELAND CAVALIERS | * | 36:28 | 18 | 6 / 19 | 4 / 11 | 2 / 8 | 4 / 4 | 8 | 1 | 5 | 2 | 1 | 2 | 5 | 22 |
| 2021-12-25 | 117 - 113 | BOSTON CELTICS @ MILWAUKEE BUCKS | * | 39:48 | 25 | 7 / 20 | 3 / 10 | 4 / 10 | 7 / 8 | 8 | 1 | 4 | 2 | 2 | 4 | 3 | 28 |
| 2022-01-05 | 97 - 99 | BOSTON CELTICS v. SAN ANTONIO SPURS | * | 37:30 | 19 | 6 / 20 | 5 / 14 | 1 / 6 | 6 / 6 | 5 | 3 | 3 | 0 | 2 | 0 | 1 | 14 |
| 2022-01-06 | 108 - 105 | BOSTON CELTICS @ NEW YORK KNICKS | * | 39:51 | 36 | 12 / 21 | 6 / 10 | 6 / 11 | 6 / 6 | 5 | 1 | 9 | 2 | 1 | 2 | 3 | 45 |
| 2022-01-08 | 99 - 75 | BOSTON CELTICS v. NEW YORK KNICKS | * | 29:26 | 19 | 6 / 14 | 3 / 6 | 3 / 8 | 4 / 4 | 3 | 0 | 1 | 1 | 0 | 2 | 0 | 18 |
| 2022-01-12 | 100 - 119 | BOSTON CELTICS @ INDIANA PACERS | * | 37:02 | 33 | 11 / 19 | 7 / 10 | 4 / 9 | 7 / 8 | 7 | 0 | 4 | 2 | 2 | 4 | 1 | 39 |
| 2022-01-14 | 111 - 99 | BOSTON CELTICS @ PHILADELPHIA 76ERS | * | 32:15 | 20 | 7 / 17 | 5 / 10 | 2 / 7 | 4 / 4 | 10 | 1 | 5 | 0 | 0 | 7 | 3 | 33 |
| 2022-01-17 | 104 - 92 | BOSTON CELTICS v. NEW ORLEANS PELICANS | * | 37:44 | 27 | 9 / 18 | 9 / 14 | 0 / 4 | 9 / 11 | 7 | 1 | 3 | 1 | 0 | 2 | 1 | 30 |
| 2022-01-19 | 102 - 111 | BOSTON CELTICS v. CHARLOTTE HORNETS | * | 35:18 | 12 | 5 / 19 | 5 / 12 | 0 / 7 | 2 / 3 | 5 | 1 | 3 | 1 | 0 | 3 | 5 | 10 |
| 2022-01-23 | 87 - 116 | BOSTON CELTICS @ WASHINGTON WIZARDS | * | 32:52 | 51 | 18 / 28 | 9 / 14 | 9 / 14 | 6 / 6 | 8 | 2 | 7 | 0 | 0 | 1 | 1 | 59 |
| 2022-01-25 | 128 - 75 | BOSTON CELTICS v. SACRAMENTO KINGS | * | 31:03 | 36 | 14 / 23 | 7 / 9 | 7 / 14 | 1 / 2 | 2 | 2 | 6 | 0 | 1 | 2 | 2 | 37 |
| 2022-01-28 | 108 - 92 | BOSTON CELTICS @ ATLANTA HAWKS | * | 35:45 | 20 | 5 / 17 | 3 / 9 | 2 / 8 | 8 / 8 | 5 | 1 | 4 | 1 | 2 | 5 | 3 | 22 |
| 2022-01-29 | 97 - 107 | BOSTON CELTICS @ NEW ORLEANS PELICANS | * | 37:27 | 38 | 17 / 26 | 13 / 13 | 4 / 13 | 0 / 0 | 8 | 0 | 7 | 3 | 0 | 2 | 3 | 49 |
| 2022-01-31 | 122 - 92 | BOSTON CELTICS v. MIAMI HEAT | * | 31:16 | 20 | 7 / 15 | 4 / 8 | 3 / 7 | 3 / 5 | 11 | 1 | 5 | 0 | 0 | 2 | 1 | 29 |
| 2022-02-02 | 113 - 107 | BOSTON CELTICS v. CHARLOTTE HORNETS | * | 32:45 | 19 | 6 / 16 | 5 / 9 | 1 / 7 | 6 / 6 | 6 | 0 | 9 | 2 | 0 | 3 | 4 | 29 |
| 2022-02-04 | 93 - 102 | BOSTON CELTICS @ DETROIT PISTONS | * | 28:08 | 24 | 9 / 21 | 5 / 12 | 4 / 9 | 2 / 3 | 8 | 1 | 1 | 1 | 0 | 2 | 0 | 24 |
| 2022-02-06 | 83 - 116 | BOSTON CELTICS @ ORLANDO MAGIC | * | 35:24 | 15 | 6 / 18 | 4 / 10 | 2 / 8 | 1 / 2 | 5 | 4 | 7 | 1 | 0 | 4 | 1 | 23 |
| 2022-02-08 | 91 - 126 | BOSTON CELTICS @ BROOKLYN NETS | * | 27:04 | 19 | 7 / 11 | 5 / 5 | 2 / 6 | 3 / 4 | 5 | 0 | 4 | 1 | 0 | 0 | 0 | 24 |
| 2022-02-11 | 108 - 102 | BOSTON CELTICS v. DENVER NUGGETS | * | 36:53 | 24 | 8 / 19 | 7 / 11 | 1 / 8 | 7 / 8 | 4 | 2 | 5 | 3 | 0 | 2 | 1 | 28 |
| 2022-02-15 | 87 - 135 | BOSTON CELTICS @ PHILADELPHIA 76ERS | * | 29:36 | 28 | 9 / 17 | 5 / 9 | 4 / 8 | 6 / 6 | 10 | 2 | 6 | 0 | 2 | 0 | 3 | 36 |
| 2022-02-16 | 111 - 112 | BOSTON CELTICS v. DETROIT PISTONS | * | 39:07 | 22 | 7 / 15 | 5 / 9 | 2 / 6 | 6 / 6 | 4 | 0 | 5 | 1 | 0 | 7 | 0 | 31 |
| 2022-02-24 | 106 - 129 | BOSTON CELTICS @ BROOKLYN NETS | * | 34:49 | 30 | 10 / 20 | 6 / 11 | 4 / 9 | 6 / 7 | 6 | 1 | 4 | 1 | 0 | 4 | 1 | 35 |
| 2022-02-26 | 104 - 113 | BOSTON CELTICS @ DETROIT PISTONS | * | 38:53 | 26 | 8 / 21 | 4 / 12 | 4 / 9 | 6 / 8 | 11 | 0 | 6 | 1 | 1 | 1 | 3 | 29 |
| 2022-02-27 | 128 - 107 | BOSTON CELTICS @ INDIANA PACERS | * | 34:17 | 24 | 7 / 22 | 5 / 10 | 2 / 12 | 8 / 8 | 3 | 2 | 3 | 1 | 0 | 2 | 4 | 20 |
| 2022-03-01 | 107 - 98 | BOSTON CELTICS v. ATLANTA HAWKS | * | 39:01 | 33 | 12 / 25 | 9 / 15 | 3 / 10 | 6 / 7 | 7 | 1 | 7 | 0 | 0 | 2 | 2 | 36 |
