| 2021-10-22 | 102 - 96 | SAN ANTONIO SPURS @ DENVER NUGGETS | * | 26:10 | 15 | 7 / 9 | 7 / 9 | 0 / 0 | 1 / 2 | 4 | 4 | 1 | 1 | 0 | 3 | 4 | 25 |
| 2021-10-23 | 111 - 121 | SAN ANTONIO SPURS v. MILWAUKEE BUCKS | * | 34:35 | 10 | 5 / 9 | 5 / 9 | 0 / 0 | 0 / 0 | 2 | 6 | 6 | 2 | 2 | 2 | 2 | 22 |
| 2021-10-26 | 121 - 125 | SAN ANTONIO SPURS v. LOS ANGELES LAKERS | * | 37:36 | 27 | 13 / 17 | 13 / 17 | 0 / 0 | 1 / 5 | 7 | 7 | 0 | 1 | 3 | 2 | 3 | 33 |
| 2021-10-28 | 104 - 99 | SAN ANTONIO SPURS @ DALLAS MAVERICKS | * | 35:48 | 14 | 7 / 13 | 7 / 13 | 0 / 0 | 0 / 2 | 7 | 6 | 2 | 1 | 2 | 1 | 3 | 21 |
| 2021-10-30 | 93 - 102 | SAN ANTONIO SPURS @ MILWAUKEE BUCKS | * | 22:42 | 8 | 3 / 6 | 3 / 6 | 0 / 0 | 2 / 2 | 4 | 2 | 1 | 1 | 0 | 1 | 5 | 14 |
| 2021-11-01 | 131 - 118 | SAN ANTONIO SPURS @ INDIANA PACERS | * | 22:01 | 11 | 5 / 9 | 5 / 9 | 0 / 0 | 1 / 2 | 3 | 3 | 1 | 0 | 1 | 2 | 1 | 14 |
| 2021-11-18 | 115 - 90 | SAN ANTONIO SPURS @ MINNESOTA TIMBERWOLVES | | 15:19 | 2 | 1 / 2 | 1 / 2 | 0 / 0 | 0 / 2 | 1 | 1 | 1 | 0 | 1 | 0 | 2 | 1 |
| 2021-11-22 | 111 - 115 | SAN ANTONIO SPURS v. PHOENIX SUNS | * | 31:15 | 15 | 7 / 9 | 7 / 9 | 0 / 0 | 1 / 6 | 4 | 5 | 2 | 0 | 0 | 2 | 4 | 21 |
| 2021-11-24 | 106 - 124 | SAN ANTONIO SPURS v. ATLANTA HAWKS | * | 29:08 | 15 | 6 / 12 | 6 / 12 | 0 / 0 | 3 / 4 | 4 | 6 | 1 | 0 | 1 | 1 | 1 | 19 |
| 2021-11-26 | 96 - 88 | SAN ANTONIO SPURS v. BOSTON CELTICS | * | 34:22 | 7 | 3 / 6 | 3 / 6 | 0 / 0 | 1 / 2 | 10 | 2 | 1 | 0 | 3 | 1 | 4 | 14 |
| 2021-11-29 | 116 - 99 | SAN ANTONIO SPURS v. WASHINGTON WIZARDS | * | 24:48 | 14 | 7 / 11 | 7 / 11 | 0 / 0 | 0 / 3 | 4 | 7 | 1 | 1 | 2 | 0 | 0 | 18 |
| 2021-12-02 | 83 - 114 | SAN ANTONIO SPURS @ PORTLAND TRAIL BLAZERS | * | 29:39 | 14 | 7 / 12 | 7 / 12 | 0 / 0 | 0 / 1 | 8 | 1 | 2 | 1 | 4 | 2 | 3 | 18 |
| 2021-12-04 | 107 - 112 | SAN ANTONIO SPURS @ GOLDEN STATE WARRIORS | * | 31:08 | 6 | 3 / 6 | 3 / 6 | 0 / 0 | 0 / 0 | 7 | 2 | 5 | 0 | 3 | 2 | 4 | 16 |
| 2021-12-06 | 108 - 104 | SAN ANTONIO SPURS @ PHOENIX SUNS | * | 32:18 | 14 | 7 / 11 | 7 / 11 | 0 / 0 | 0 / 0 | 8 | 3 | 2 | 0 | 1 | 3 | 3 | 25 |
| 2021-12-07 | 109 - 121 | SAN ANTONIO SPURS v. NEW YORK KNICKS | * | 29:46 | 13 | 6 / 11 | 6 / 11 | 0 / 0 | 1 / 3 | 4 | 4 | 5 | 0 | 3 | 0 | 4 | 16 |
| 2021-12-09 | 123 - 111 | SAN ANTONIO SPURS v. DENVER NUGGETS | * | 29:37 | 9 | 4 / 7 | 4 / 7 | 0 / 0 | 1 / 3 | 3 | 6 | 7 | 0 | 2 | 2 | 5 | 20 |
| 2021-12-11 | 112 - 127 | SAN ANTONIO SPURS v. DENVER NUGGETS | * | 17:34 | 6 | 2 / 4 | 2 / 4 | 0 / 0 | 2 / 5 | 0 | 2 | 4 | 0 | 1 | 3 | 3 | 9 |
| 2021-12-12 | 112 - 97 | SAN ANTONIO SPURS v. NEW ORLEANS PELICANS | * | 34:10 | 24 | 10 / 12 | 10 / 12 | 0 / 0 | 4 / 9 | 5 | 7 | 3 | 1 | 2 | 4 | 4 | 35 |
| 2021-12-15 | 115 - 131 | SAN ANTONIO SPURS v. CHARLOTTE HORNETS | * | 24:39 | 9 | 4 / 7 | 4 / 7 | 0 / 0 | 1 / 1 | 2 | 2 | 0 | 1 | 0 | 0 | 2 | 11 |
| 2021-12-17 | 126 - 128 | SAN ANTONIO SPURS @ UTAH JAZZ | * | 32:54 | 14 | 7 / 12 | 7 / 12 | 0 / 0 | 0 / 0 | 2 | 3 | 3 | 1 | 2 | 1 | 3 | 17 |
| 2021-12-19 | 121 - 114 | SAN ANTONIO SPURS @ SACRAMENTO KINGS | * | 33:48 | 4 | 2 / 10 | 2 / 10 | 0 / 0 | 0 / 0 | 3 | 5 | 3 | 1 | 2 | 1 | 3 | 7 |
| 2021-12-20 | 92 - 116 | SAN ANTONIO SPURS @ LOS ANGELES CLIPPERS | * | 29:33 | 17 | 8 / 13 | 8 / 13 | 0 / 0 | 1 / 3 | 6 | 5 | 5 | 3 | 2 | 2 | 6 | 29 |
| 2021-12-23 | 110 - 138 | SAN ANTONIO SPURS @ LOS ANGELES LAKERS | * | 20:59 | 8 | 4 / 8 | 4 / 8 | 0 / 0 | 0 / 0 | 1 | 2 | 2 | 0 | 0 | 0 | 5 | 9 |
| 2021-12-26 | 144 - 109 | SAN ANTONIO SPURS v. DETROIT PISTONS | * | 15:20 | 14 | 7 / 8 | 7 / 8 | 0 / 0 | 0 / 0 | 2 | 2 | 2 | 0 | 0 | 3 | 3 | 22 |
| 2021-12-27 | 104 - 110 | SAN ANTONIO SPURS v. UTAH JAZZ | * | 27:15 | 10 | 5 / 11 | 5 / 11 | 0 / 0 | 0 / 2 | 9 | 4 | 5 | 1 | 0 | 2 | 5 | 23 |
| 2021-12-31 | 118 - 105 | SAN ANTONIO SPURS @ MEMPHIS GRIZZLIES | * | 24:11 | 15 | 7 / 12 | 7 / 12 | 0 / 0 | 1 / 4 | 3 | 4 | 1 | 0 | 2 | 0 | 0 | 13 |
| 2022-01-01 | 117 - 116 | SAN ANTONIO SPURS @ DETROIT PISTONS | * | 36:20 | 15 | 6 / 11 | 6 / 11 | 0 / 0 | 3 / 6 | 7 | 5 | 5 | 1 | 1 | 6 | 5 | 30 |
| 2022-01-04 | 129 - 104 | SAN ANTONIO SPURS @ TORONTO RAPTORS | * | 22:38 | 19 | 9 / 13 | 9 / 13 | 0 / 0 | 1 / 5 | 8 | 4 | 4 | 0 | 0 | 2 | 0 | 29 |
| 2022-01-05 | 97 - 99 | SAN ANTONIO SPURS @ BOSTON CELTICS | * | 35:07 | 8 | 4 / 7 | 4 / 7 | 0 / 0 | 0 / 0 | 12 | 2 | 1 | 1 | 1 | 1 | 2 | 21 |
| 2022-01-07 | 119 - 100 | SAN ANTONIO SPURS @ PHILADELPHIA 76ERS | * | 29:47 | 17 | 7 / 12 | 7 / 12 | 0 / 0 | 3 / 4 | 4 | 2 | 1 | 1 | 1 | 0 | 2 | 18 |
| 2022-01-09 | 121 - 119 | SAN ANTONIO SPURS @ BROOKLYN NETS | * | 36:17 | 11 | 5 / 10 | 5 / 10 | 0 / 0 | 1 / 3 | 5 | 7 | 3 | 3 | 2 | 1 | 4 | 21 |
| 2022-01-10 | 111 - 96 | SAN ANTONIO SPURS @ NEW YORK KNICKS | * | 24:07 | 12 | 6 / 12 | 6 / 12 | 0 / 0 | 0 / 1 | 3 | 7 | 3 | 0 | 2 | 3 | 3 | 19 |
| 2022-01-12 | 124 - 128 | SAN ANTONIO SPURS v. HOUSTON ROCKETS | * | 31:26 | 13 | 4 / 5 | 4 / 5 | 0 / 0 | 5 / 7 | 3 | 3 | 3 | 2 | 2 | 2 | 6 | 21 |
| 2022-01-14 | 109 - 114 | SAN ANTONIO SPURS v. CLEVELAND CAVALIERS | * | 32:49 | 0 | 0 / 4 | 0 / 4 | 0 / 0 | 0 / 0 | 11 | 1 | 2 | 2 | 3 | 1 | 4 | 10 |
| 2022-01-17 | 107 - 121 | SAN ANTONIO SPURS v. PHOENIX SUNS | * | 29:36 | 23 | 9 / 12 | 9 / 12 | 0 / 0 | 5 / 7 | 8 | 6 | 4 | 0 | 2 | 3 | 0 | 37 |
| 2022-01-19 | 118 - 96 | SAN ANTONIO SPURS v. OKLAHOMA CITY THUNDER | * | 26:26 | 13 | 6 / 9 | 6 / 9 | 0 / 0 | 1 / 2 | 5 | 3 | 4 | 1 | 4 | 1 | 1 | 19 |
| 2022-01-21 | 102 - 117 | SAN ANTONIO SPURS v. BROOKLYN NETS | * | 35:45 | 15 | 6 / 12 | 6 / 12 | 0 / 0 | 3 / 5 | 6 | 5 | 1 | 0 | 3 | 0 | 2 | 16 |
| 2022-01-23 | 109 - 115 | SAN ANTONIO SPURS v. PHILADELPHIA 76ERS | * | 39:01 | 25 | 11 / 16 | 11 / 16 | 0 / 0 | 3 / 4 | 6 | 4 | 2 | 0 | 4 | 1 | 4 | 28 |
| 2022-01-25 | 104 - 134 | SAN ANTONIO SPURS @ HOUSTON ROCKETS | * | 20:51 | 18 | 9 / 13 | 9 / 13 | 0 / 0 | 0 / 0 | 7 | 2 | 3 | 0 | 2 | 1 | 1 | 25 |
| 2022-01-26 | 110 - 118 | SAN ANTONIO SPURS v. MEMPHIS GRIZZLIES | * | 32:51 | 18 | 8 / 8 | 8 / 8 | 0 / 0 | 2 / 4 | 3 | 4 | 5 | 2 | 4 | 0 | 5 | 26 |
| 2022-01-28 | 131 - 122 | SAN ANTONIO SPURS v. CHICAGO BULLS | * | 32:02 | 21 | 9 / 12 | 9 / 12 | 0 / 0 | 3 / 5 | 5 | 6 | 4 | 0 | 1 | 0 | 4 | 30 |
| 2022-02-01 | 120 - 124 | SAN ANTONIO SPURS v. GOLDEN STATE WARRIORS | * | 12:18 | 7 | 3 / 4 | 3 / 4 | 0 / 0 | 1 / 2 | 3 | 2 | 1 | 1 | 1 | 1 | 2 | 12 |
| 2022-02-04 | 131 - 106 | SAN ANTONIO SPURS v. HOUSTON ROCKETS | * | 32:45 | 21 | 9 / 15 | 9 / 15 | 0 / 0 | 3 / 4 | 8 | 2 | 3 | 1 | 3 | 2 | 2 | 27 |
| 2022-02-09 | 105 - 92 | SAN ANTONIO SPURS @ CLEVELAND CAVALIERS | * | 28:32 | 7 | 3 / 5 | 3 / 5 | 0 / 0 | 1 / 2 | 7 | 4 | 2 | 2 | 3 | 4 | 2 | 20 |
| 2022-02-11 | 121 - 136 | SAN ANTONIO SPURS @ ATLANTA HAWKS | * | 27:20 | 12 | 4 / 7 | 3 / 6 | 1 / 1 | 3 / 4 | 5 | 0 | 3 | 1 | 3 | 3 | 2 | 17 |
| 2022-02-12 | 114 - 124 | SAN ANTONIO SPURS @ NEW ORLEANS PELICANS | * | 29:15 | 7 | 3 / 7 | 3 / 7 | 0 / 0 | 1 / 2 | 6 | 5 | 2 | 2 | 4 | 0 | 5 | 13 |
| 2022-02-14 | 120 - 109 | SAN ANTONIO SPURS @ CHICAGO BULLS | * | 30:12 | 13 | 6 / 9 | 6 / 9 | 0 / 0 | 1 / 2 | 8 | 1 | 4 | 0 | 0 | 2 | 3 | 24 |
| 2022-02-16 | 106 - 114 | SAN ANTONIO SPURS @ OKLAHOMA CITY THUNDER | * | 31:38 | 20 | 10 / 14 | 10 / 14 | 0 / 0 | 0 / 1 | 11 | 6 | 5 | 0 | 2 | 3 | 4 | 38 |
| 2022-02-28 | 118 - 105 | SAN ANTONIO SPURS @ MEMPHIS GRIZZLIES | * | 32:23 | 16 | 8 / 11 | 8 / 11 | 0 / 0 | 0 / 2 | 6 | 4 | 4 | 2 | 1 | 3 | 4 | 29 |
| 2022-03-03 | 112 - 115 | SAN ANTONIO SPURS v. SACRAMENTO KINGS | * | 33:18 | 16 | 8 / 14 | 8 / 14 | 0 / 0 | 0 / 0 | 5 | 2 | 4 | 1 | 2 | 0 | 4 | 20 |