| 2021-10-22 | 102 - 96 | SAN ANTONIO SPURS @ DENVER NUGGETS | * | 34:53 | 15 | 7 / 18 | 6 / 14 | 1 / 4 | 0 / 0 | 8 | 1 | 6 | 2 | 0 | 4 | 4 | 25 |
| 2021-10-23 | 111 - 121 | SAN ANTONIO SPURS v. MILWAUKEE BUCKS | * | 34:25 | 10 | 5 / 14 | 5 / 12 | 0 / 2 | 0 / 0 | 9 | 0 | 7 | 1 | 0 | 0 | 2 | 18 |
| 2021-10-28 | 104 - 99 | SAN ANTONIO SPURS @ DALLAS MAVERICKS | * | 35:36 | 23 | 10 / 17 | 7 / 12 | 3 / 5 | 0 / 0 | 8 | 2 | 8 | 1 | 0 | 2 | 1 | 37 |
| 2021-10-30 | 93 - 102 | SAN ANTONIO SPURS @ MILWAUKEE BUCKS | * | 36:40 | 23 | 9 / 17 | 8 / 14 | 1 / 3 | 4 / 5 | 5 | 0 | 9 | 3 | 0 | 2 | 1 | 33 |
| 2021-11-01 | 131 - 118 | SAN ANTONIO SPURS @ INDIANA PACERS | * | 26:16 | 16 | 6 / 10 | 3 / 5 | 3 / 5 | 1 / 2 | 2 | 0 | 6 | 1 | 0 | 0 | 1 | 20 |
| 2021-11-03 | 108 - 109 | SAN ANTONIO SPURS v. DALLAS MAVERICKS | * | 34:26 | 23 | 8 / 18 | 6 / 11 | 2 / 7 | 5 / 6 | 9 | 0 | 8 | 2 | 1 | 3 | 4 | 33 |
| 2021-11-05 | 89 - 102 | SAN ANTONIO SPURS @ ORLANDO MAGIC | * | 36:00 | 20 | 9 / 16 | 8 / 14 | 1 / 2 | 1 / 1 | 11 | 0 | 7 | 3 | 1 | 3 | 1 | 36 |
| 2021-11-07 | 99 - 94 | SAN ANTONIO SPURS @ OKLAHOMA CITY THUNDER | * | 35:28 | 10 | 5 / 19 | 5 / 15 | 0 / 4 | 0 / 0 | 7 | 1 | 9 | 3 | 1 | 3 | 2 | 18 |
| 2021-11-10 | 136 - 117 | SAN ANTONIO SPURS v. SACRAMENTO KINGS | * | 32:00 | 26 | 11 / 21 | 9 / 16 | 2 / 5 | 2 / 2 | 6 | 0 | 7 | 2 | 0 | 1 | 3 | 32 |
| 2021-11-12 | 109 - 123 | SAN ANTONIO SPURS v. DALLAS MAVERICKS | * | 31:16 | 15 | 7 / 14 | 7 / 12 | 0 / 2 | 1 / 2 | 5 | 0 | 4 | 0 | 0 | 3 | 1 | 19 |
| 2021-11-14 | 114 - 106 | SAN ANTONIO SPURS @ LOS ANGELES LAKERS | * | 38:12 | 22 | 9 / 20 | 7 / 15 | 2 / 5 | 2 / 4 | 9 | 1 | 10 | 3 | 1 | 3 | 1 | 34 |
| 2021-11-16 | 106 - 92 | SAN ANTONIO SPURS @ LOS ANGELES CLIPPERS | * | 38:32 | 26 | 12 / 21 | 11 / 19 | 1 / 2 | 1 / 2 | 10 | 2 | 9 | 3 | 0 | 4 | 1 | 44 |
| 2021-11-18 | 115 - 90 | SAN ANTONIO SPURS @ MINNESOTA TIMBERWOLVES | * | 32:01 | 7 | 2 / 12 | 2 / 8 | 0 / 4 | 3 / 4 | 6 | 2 | 4 | 0 | 1 | 3 | 3 | 10 |
| 2021-11-22 | 111 - 115 | SAN ANTONIO SPURS v. PHOENIX SUNS | * | 37:21 | 18 | 9 / 22 | 9 / 19 | 0 / 3 | 0 / 1 | 10 | 0 | 11 | 3 | 1 | 1 | 2 | 28 |
| 2021-11-24 | 106 - 124 | SAN ANTONIO SPURS v. ATLANTA HAWKS | * | 33:47 | 22 | 9 / 20 | 5 / 13 | 4 / 7 | 0 / 0 | 6 | 2 | 11 | 2 | 0 | 3 | 1 | 35 |
| 2021-11-26 | 96 - 88 | SAN ANTONIO SPURS v. BOSTON CELTICS | * | 37:43 | 29 | 12 / 24 | 12 / 22 | 0 / 2 | 5 / 7 | 10 | 1 | 6 | 3 | 1 | 3 | 2 | 37 |
| 2021-11-29 | 116 - 99 | SAN ANTONIO SPURS v. WASHINGTON WIZARDS | * | 34:07 | 22 | 8 / 19 | 8 / 17 | 0 / 2 | 6 / 7 | 8 | 2 | 8 | 0 | 0 | 1 | 1 | 29 |
| 2021-12-02 | 83 - 114 | SAN ANTONIO SPURS @ PORTLAND TRAIL BLAZERS | * | 34:30 | 15 | 6 / 16 | 3 / 9 | 3 / 7 | 0 / 0 | 7 | 0 | 13 | 2 | 0 | 2 | 3 | 29 |
| 2021-12-04 | 107 - 112 | SAN ANTONIO SPURS @ GOLDEN STATE WARRIORS | * | 36:36 | 23 | 10 / 21 | 7 / 14 | 3 / 7 | 0 / 0 | 7 | 5 | 7 | 2 | 0 | 4 | 4 | 37 |
| 2021-12-06 | 108 - 104 | SAN ANTONIO SPURS @ PHOENIX SUNS | * | 33:49 | 17 | 7 / 12 | 5 / 10 | 2 / 2 | 1 / 2 | 5 | 1 | 14 | 2 | 0 | 4 | 2 | 37 |
| 2021-12-07 | 109 - 121 | SAN ANTONIO SPURS v. NEW YORK KNICKS | * | 34:52 | 15 | 6 / 15 | 4 / 10 | 2 / 5 | 1 / 1 | 7 | 0 | 7 | 1 | 0 | 0 | 1 | 21 |
| 2021-12-09 | 123 - 111 | SAN ANTONIO SPURS v. DENVER NUGGETS | * | 34:59 | 20 | 7 / 16 | 4 / 8 | 3 / 8 | 3 / 4 | 5 | 3 | 9 | 1 | 0 | 5 | 3 | 33 |
| 2021-12-11 | 112 - 127 | SAN ANTONIO SPURS v. DENVER NUGGETS | * | 22:48 | 6 | 3 / 9 | 3 / 8 | 0 / 1 | 0 / 0 | 5 | 0 | 4 | 2 | 1 | 5 | 2 | 15 |
| 2021-12-12 | 112 - 97 | SAN ANTONIO SPURS v. NEW ORLEANS PELICANS | * | 33:44 | 10 | 5 / 13 | 5 / 11 | 0 / 2 | 0 / 0 | 11 | 1 | 10 | 3 | 0 | 1 | 2 | 28 |
| 2021-12-15 | 115 - 131 | SAN ANTONIO SPURS v. CHARLOTTE HORNETS | * | 34:57 | 10 | 4 / 11 | 2 / 6 | 2 / 5 | 0 / 0 | 5 | 1 | 9 | 1 | 0 | 1 | 1 | 20 |
| 2021-12-17 | 126 - 128 | SAN ANTONIO SPURS @ UTAH JAZZ | * | 36:35 | 16 | 6 / 16 | 5 / 10 | 1 / 6 | 3 / 6 | 7 | 4 | 11 | 2 | 1 | 2 | 1 | 28 |
| 2021-12-19 | 121 - 114 | SAN ANTONIO SPURS @ SACRAMENTO KINGS | * | 35:11 | 25 | 11 / 17 | 11 / 17 | 0 / 0 | 3 / 4 | 7 | 0 | 9 | 1 | 0 | 2 | 2 | 37 |
| 2021-12-20 | 92 - 116 | SAN ANTONIO SPURS @ LOS ANGELES CLIPPERS | * | 31:13 | 24 | 10 / 22 | 6 / 16 | 4 / 6 | 0 / 0 | 8 | 3 | 13 | 5 | 0 | 2 | 2 | 43 |
| 2021-12-23 | 110 - 138 | SAN ANTONIO SPURS @ LOS ANGELES LAKERS | * | 32:21 | 9 | 3 / 16 | 2 / 11 | 1 / 5 | 2 / 2 | 4 | 2 | 13 | 2 | 2 | 0 | 1 | 15 |
| 2022-01-05 | 97 - 99 | SAN ANTONIO SPURS @ BOSTON CELTICS | * | 32:51 | 22 | 11 / 21 | 11 / 19 | 0 / 2 | 0 / 0 | 7 | 2 | 12 | 3 | 0 | 4 | 1 | 40 |
| 2022-01-07 | 119 - 100 | SAN ANTONIO SPURS @ PHILADELPHIA 76ERS | * | 35:35 | 27 | 10 / 23 | 7 / 17 | 3 / 6 | 4 / 5 | 4 | 1 | 9 | 3 | 1 | 6 | 3 | 35 |
| 2022-01-09 | 121 - 119 | SAN ANTONIO SPURS @ BROOKLYN NETS | * | 39:31 | 19 | 7 / 22 | 6 / 16 | 1 / 6 | 4 / 4 | 9 | 0 | 12 | 2 | 1 | 3 | 2 | 29 |
| 2022-01-10 | 111 - 96 | SAN ANTONIO SPURS @ NEW YORK KNICKS | * | 30:22 | 24 | 11 / 19 | 10 / 14 | 1 / 5 | 1 / 1 | 2 | 2 | 5 | 2 | 1 | 3 | 3 | 29 |
| 2022-01-12 | 124 - 128 | SAN ANTONIO SPURS v. HOUSTON ROCKETS | * | 36:45 | 32 | 12 / 26 | 8 / 17 | 4 / 9 | 4 / 7 | 7 | 3 | 11 | 3 | 0 | 0 | 5 | 39 |
| 2022-01-14 | 109 - 114 | SAN ANTONIO SPURS v. CLEVELAND CAVALIERS | * | 35:38 | 30 | 14 / 23 | 13 / 19 | 1 / 4 | 1 / 3 | 12 | 2 | 8 | 0 | 0 | 2 | 3 | 43 |
| 2022-01-15 | 101 - 94 | SAN ANTONIO SPURS v. LOS ANGELES CLIPPERS | * | 36:08 | 18 | 8 / 17 | 8 / 14 | 0 / 3 | 2 / 2 | 6 | 1 | 9 | 3 | 0 | 3 | 0 | 31 |
| 2022-01-17 | 107 - 121 | SAN ANTONIO SPURS v. PHOENIX SUNS | * | 31:46 | 18 | 7 / 16 | 5 / 11 | 2 / 5 | 2 / 2 | 8 | 0 | 4 | 0 | 0 | 2 | 1 | 23 |
| 2022-01-19 | 118 - 96 | SAN ANTONIO SPURS v. OKLAHOMA CITY THUNDER | * | 30:15 | 23 | 11 / 20 | 10 / 14 | 1 / 6 | 0 / 0 | 7 | 3 | 14 | 3 | 0 | 1 | 0 | 42 |
| 2022-01-21 | 102 - 117 | SAN ANTONIO SPURS v. BROOKLYN NETS | * | 37:11 | 25 | 8 / 20 | 7 / 17 | 1 / 3 | 8 / 8 | 8 | 4 | 10 | 1 | 0 | 1 | 3 | 37 |
| 2022-01-23 | 109 - 115 | SAN ANTONIO SPURS v. PHILADELPHIA 76ERS | * | 38:26 | 19 | 6 / 14 | 6 / 12 | 0 / 2 | 7 / 10 | 7 | 2 | 12 | 1 | 0 | 4 | 2 | 34 |
| 2022-01-25 | 104 - 134 | SAN ANTONIO SPURS @ HOUSTON ROCKETS | * | 24:10 | 19 | 8 / 15 | 7 / 10 | 1 / 5 | 2 / 2 | 5 | 0 | 10 | 3 | 0 | 2 | 4 | 32 |
| 2022-01-26 | 110 - 118 | SAN ANTONIO SPURS v. MEMPHIS GRIZZLIES | * | 38:57 | 16 | 5 / 17 | 5 / 14 | 0 / 3 | 6 / 7 | 6 | 4 | 11 | 2 | 0 | 3 | 3 | 29 |
| 2022-01-28 | 131 - 122 | SAN ANTONIO SPURS v. CHICAGO BULLS | * | 36:35 | 29 | 12 / 24 | 10 / 20 | 2 / 4 | 3 / 4 | 9 | 0 | 12 | 3 | 0 | 5 | 2 | 45 |
| 2022-02-01 | 120 - 124 | SAN ANTONIO SPURS v. GOLDEN STATE WARRIORS | * | 37:33 | 27 | 12 / 21 | 11 / 18 | 1 / 3 | 2 / 3 | 8 | 1 | 9 | 2 | 1 | 6 | 1 | 42 |
| 2022-02-04 | 131 - 106 | SAN ANTONIO SPURS v. HOUSTON ROCKETS | * | 35:11 | 19 | 9 / 16 | 8 / 12 | 1 / 4 | 0 / 0 | 6 | 1 | 11 | 4 | 0 | 1 | 3 | 35 |
| 2022-02-09 | 105 - 92 | SAN ANTONIO SPURS @ CLEVELAND CAVALIERS | * | 33:52 | 16 | 7 / 17 | 7 / 16 | 0 / 1 | 2 / 2 | 4 | 2 | 9 | 0 | 0 | 2 | 2 | 23 |
| 2022-02-11 | 121 - 136 | SAN ANTONIO SPURS @ ATLANTA HAWKS | * | 31:49 | 32 | 11 / 18 | 9 / 13 | 2 / 5 | 8 / 9 | 9 | 1 | 15 | 4 | 0 | 1 | 2 | 54 |
| 2022-02-12 | 114 - 124 | SAN ANTONIO SPURS @ NEW ORLEANS PELICANS | * | 34:40 | 31 | 13 / 22 | 11 / 18 | 2 / 4 | 3 / 3 | 7 | 0 | 12 | 2 | 0 | 1 | 0 | 44 |
| 2022-02-14 | 120 - 109 | SAN ANTONIO SPURS @ CHICAGO BULLS | * | 35:57 | 19 | 7 / 16 | 7 / 15 | 0 / 1 | 5 / 7 | 6 | 0 | 11 | 2 | 0 | 2 | 3 | 29 |
| 2022-02-16 | 106 - 114 | SAN ANTONIO SPURS @ OKLAHOMA CITY THUNDER | * | 35:57 | 18 | 8 / 18 | 7 / 15 | 1 / 3 | 1 / 1 | 5 | 2 | 8 | 1 | 0 | 1 | 1 | 25 |
