| 2021-09-13 | 108 - 111 | CACIQUES DE HUMACAO v. GIGANTES DE CAROLINA | * | 37:34 | 34 | 11 / 24 | 9 / 15 | 2 / 9 | 10 / 11 | 3 | 0 | 4 | 6 | 3 | 1 | 3 | 31 |
| 2021-09-16 | 100 - 90 | CACIQUES DE HUMACAO @ CANGREJEROS DE SANTURCE | * | 31:16 | 18 | 5 / 11 | 4 / 8 | 1 / 3 | 7 / 7 | 3 | 0 | 4 | 3 | 3 | 0 | 4 | 19 |
| 2021-09-18 | 102 - 105 | CACIQUES DE HUMACAO v. METS DE GUAYNABO | * | 39:39 | 27 | 6 / 17 | 3 / 12 | 3 / 5 | 12 / 13 | 7 | 3 | 4 | 0 | 3 | 0 | 3 | 26 |
| 2021-09-22 | 102 - 60 | CACIQUES DE HUMACAO @ BRUJOS DE GUAYAMA | * | 18:31 | 8 | 4 / 12 | 4 / 7 | 0 / 5 | 0 / 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 3 |
| 2021-09-24 | 97 - 109 | CACIQUES DE HUMACAO v. ATLETICOS DE SAN GERMAN | * | 39:06 | 27 | 9 / 22 | 7 / 14 | 2 / 8 | 7 / 8 | 4 | 3 | 3 | 1 | 3 | 0 | 4 | 21 |
| 2021-09-25 | 82 - 90 | CACIQUES DE HUMACAO v. CARIDUROS DE FAJARDO | * | 33:49 | 19 | 6 / 12 | 6 / 8 | 0 / 4 | 7 / 9 | 6 | 1 | 1 | 0 | 7 | 0 | 0 | 12 |
| 2021-09-30 | 103 - 88 | CACIQUES DE HUMACAO @ METS DE GUAYNABO | * | 26:15 | 13 | 4 / 9 | 3 / 7 | 1 / 2 | 4 / 4 | 3 | 0 | 5 | 1 | 1 | 0 | 1 | 16 |
| 2021-10-02 | 91 - 101 | CACIQUES DE HUMACAO v. VAQUEROS DE BAYAMON | * | 34:04 | 25 | 9 / 16 | 7 / 13 | 2 / 3 | 5 / 5 | 4 | 4 | 2 | 2 | 3 | 0 | 2 | 27 |
| 2021-10-05 | 88 - 92 | CACIQUES DE HUMACAO @ CANGREJEROS DE SANTURCE | * | 32:50 | 22 | 7 / 17 | 5 / 12 | 2 / 5 | 6 / 8 | 3 | 0 | 0 | 2 | 4 | 0 | 2 | 11 |
| 2021-10-06 | 126 - 136 | CACIQUES DE HUMACAO @ GIGANTES DE CAROLINA | * | 37:25 | 25 | 10 / 17 | 8 / 13 | 2 / 4 | 3 / 5 | 5 | 3 | 4 | 0 | 5 | 0 | 2 | 23 |
