| 2022-02-04 | 131 - 106 | SAN ANTONIO SPURS v. HOUSTON ROCKETS | | 13:21 | 10 | 4 / 7 | 3 / 6 | 1 / 1 | 1 / 2 | 3 | 4 | 3 | 2 | 0 | 2 | 2 | 20 |
| 2022-02-09 | 105 - 92 | SAN ANTONIO SPURS @ CLEVELAND CAVALIERS | | 17:56 | 5 | 2 / 6 | 2 / 5 | 0 / 1 | 1 / 2 | 4 | 3 | 3 | 1 | 0 | 2 | 4 | 13 |
| 2022-02-11 | 121 - 136 | SAN ANTONIO SPURS @ ATLANTA HAWKS | | 16:30 | 5 | 2 / 6 | 1 / 5 | 1 / 1 | 0 / 0 | 4 | 0 | 2 | 0 | 0 | 1 | 1 | 8 |
| 2022-02-14 | 120 - 109 | SAN ANTONIO SPURS @ CHICAGO BULLS | | 17:48 | 9 | 4 / 6 | 3 / 3 | 1 / 3 | 0 / 0 | 2 | 0 | 2 | 1 | 1 | 0 | 2 | 11 |
| 2022-02-16 | 106 - 114 | SAN ANTONIO SPURS @ OKLAHOMA CITY THUNDER | | 16:12 | 0 | 0 / 2 | 0 / 1 | 0 / 1 | 0 / 0 | 5 | 1 | 1 | 0 | 1 | 3 | 2 | 7 |
| 2022-02-25 | 153 - 157 | SAN ANTONIO SPURS @ WASHINGTON WIZARDS | | 16:05 | 4 | 2 / 5 | 2 / 3 | 0 / 2 | 0 / 0 | 0 | 3 | 1 | 2 | 1 | 2 | 2 | 8 |
| 2022-02-26 | 133 - 129 | SAN ANTONIO SPURS @ MIAMI HEAT | * | 17:08 | 5 | 2 / 4 | 2 / 4 | 0 / 0 | 1 / 2 | 4 | 3 | 2 | 0 | 0 | 5 | 3 | 16 |
| 2022-02-28 | 118 - 105 | SAN ANTONIO SPURS @ MEMPHIS GRIZZLIES | | 15:37 | 6 | 1 / 3 | 1 / 1 | 0 / 2 | 4 / 4 | 4 | 1 | 1 | 0 | 0 | 3 | 2 | 13 |
| 2022-03-03 | 112 - 115 | SAN ANTONIO SPURS v. SACRAMENTO KINGS | | 14:38 | 4 | 2 / 2 | 2 / 2 | 0 / 0 | 0 / 0 | 4 | 1 | 3 | 0 | 0 | 1 | 2 | 13 |
| 2022-03-05 | 123 - 117 | SAN ANTONIO SPURS @ CHARLOTTE HORNETS | | 18:11 | 5 | 2 / 3 | 1 / 2 | 1 / 1 | 0 / 0 | 8 | 2 | 2 | 0 | 3 | 1 | 4 | 14 |
| 2022-03-07 | 117 - 110 | SAN ANTONIO SPURS v. LOS ANGELES LAKERS | | 9:25 | 3 | 1 / 3 | 1 / 3 | 0 / 0 | 1 / 2 | 0 | 3 | 0 | 0 | 0 | 0 | 2 | 3 |
| 2022-03-09 | 104 - 119 | SAN ANTONIO SPURS v. TORONTO RAPTORS | | 10:13 | 4 | 0 / 0 | 0 / 0 | 0 / 0 | 4 / 4 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4 |
| 2022-03-11 | 104 - 102 | SAN ANTONIO SPURS v. UTAH JAZZ | | 19:17 | 15 | 4 / 7 | 2 / 4 | 2 / 3 | 5 / 5 | 2 | 3 | 3 | 0 | 1 | 1 | 2 | 20 |
| 2022-03-12 | 108 - 119 | SAN ANTONIO SPURS v. INDIANA PACERS | * | 20:17 | 9 | 3 / 5 | 2 / 4 | 1 / 1 | 2 / 2 | 3 | 2 | 2 | 0 | 1 | 1 | 4 | 14 |
| 2022-03-14 | 139 - 149 | SAN ANTONIO SPURS v. MINNESOTA TIMBERWOLVES | | 19:16 | 5 | 2 / 7 | 1 / 3 | 1 / 4 | 0 / 0 | 4 | 1 | 2 | 0 | 4 | 2 | 3 | 5 |
| 2022-03-16 | 122 - 120 | SAN ANTONIO SPURS v. OKLAHOMA CITY THUNDER | | 14:41 | 7 | 3 / 5 | 2 / 4 | 1 / 1 | 0 / 0 | 3 | 1 | 1 | 0 | 1 | 0 | 3 | 9 |
| 2022-03-18 | 91 - 124 | SAN ANTONIO SPURS v. NEW ORLEANS PELICANS | | 16:29 | 2 | 1 / 10 | 1 / 5 | 0 / 5 | 0 / 0 | 4 | 1 | 3 | 0 | 1 | 3 | 1 | 3 |
| 2022-03-20 | 108 - 110 | SAN ANTONIO SPURS @ GOLDEN STATE WARRIORS | | 19:26 | 11 | 4 / 8 | 2 / 5 | 2 / 3 | 1 / 2 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 10 |
| 2022-03-23 | 96 - 133 | SAN ANTONIO SPURS @ PORTLAND TRAIL BLAZERS | | 22:47 | 8 | 3 / 6 | 3 / 4 | 0 / 2 | 2 / 2 | 7 | 2 | 3 | 0 | 2 | 2 | 3 | 17 |
| 2022-03-26 | 103 - 107 | SAN ANTONIO SPURS @ NEW ORLEANS PELICANS | | 17:48 | 10 | 3 / 7 | 3 / 7 | 0 / 0 | 4 / 4 | 3 | 2 | 3 | 0 | 0 | 1 | 3 | 15 |
| 2022-03-28 | 120 - 123 | SAN ANTONIO SPURS @ HOUSTON ROCKETS | | 21:10 | 13 | 6 / 10 | 6 / 8 | 0 / 2 | 1 / 2 | 4 | 4 | 3 | 1 | 0 | 1 | 2 | 21 |
| 2022-03-30 | 111 - 112 | SAN ANTONIO SPURS v. MEMPHIS GRIZZLIES | | 13:49 | 4 | 2 / 3 | 2 / 3 | 0 / 0 | 0 / 0 | 2 | 0 | 2 | 0 | 0 | 1 | 4 | 8 |
| 2022-04-01 | 130 - 111 | SAN ANTONIO SPURS v. PORTLAND TRAIL BLAZERS | | 24:59 | 15 | 3 / 5 | 3 / 4 | 0 / 1 | 9 / 12 | 8 | 1 | 5 | 2 | 2 | 2 | 3 | 26 |
| 2022-04-03 | 113 - 92 | SAN ANTONIO SPURS v. PORTLAND TRAIL BLAZERS | * | 30:46 | 18 | 5 / 9 | 4 / 6 | 1 / 3 | 7 / 10 | 9 | 4 | 2 | 0 | 0 | 5 | 2 | 31 |
| 2022-04-05 | 97 - 116 | SAN ANTONIO SPURS @ DENVER NUGGETS | | 25:05 | 13 | 6 / 11 | 6 / 11 | 0 / 0 | 1 / 1 | 4 | 3 | 3 | 1 | 0 | 1 | 2 | 20 |
| 2022-04-07 | 127 - 121 | SAN ANTONIO SPURS @ MINNESOTA TIMBERWOLVES | | 15:55 | 13 | 4 / 7 | 2 / 4 | 2 / 3 | 3 / 3 | 3 | 0 | 1 | 0 | 1 | 1 | 1 | 14 |
| 2022-04-09 | 94 - 100 | SAN ANTONIO SPURS v. GOLDEN STATE WARRIORS | * | 22:03 | 7 | 2 / 5 | 2 / 4 | 0 / 1 | 3 / 4 | 11 | 0 | 2 | 0 | 3 | 2 | 4 | 15 |
| 2022-04-10 | 130 - 120 | SAN ANTONIO SPURS @ DALLAS MAVERICKS | | 15:10 | 8 | 3 / 3 | 3 / 3 | 0 / 0 | 2 / 2 | 2 | 0 | 4 | 3 | 1 | 1 | 3 | 17 |
