| 2021-10-22 | 105 - 115 | LOS ANGELES LAKERS v. PHOENIX SUNS | * | 34:35 | 15 | 6 / 15 | 6 / 12 | 0 / 3 | 3 / 8 | 9 | 2 | 9 | 2 | 1 | 4 | 5 | 26 |
| 2021-10-24 | 121 - 118 | LOS ANGELES LAKERS v. MEMPHIS GRIZZLIES | * | 36:46 | 13 | 5 / 15 | 4 / 11 | 1 / 4 | 2 / 4 | 6 | 1 | 13 | 4 | 0 | 9 | 3 | 34 |
| 2021-10-26 | 121 - 125 | LOS ANGELES LAKERS @ SAN ANTONIO SPURS | * | 39:37 | 33 | 15 / 27 | 14 / 23 | 1 / 4 | 2 / 4 | 10 | 0 | 8 | 3 | 0 | 3 | 5 | 43 |
| 2021-10-27 | 123 - 115 | LOS ANGELES LAKERS @ OKLAHOMA CITY THUNDER | * | 34:50 | 20 | 8 / 20 | 6 / 12 | 2 / 8 | 2 / 3 | 10 | 4 | 13 | 1 | 0 | 10 | 4 | 45 |
| 2021-10-29 | 113 - 101 | LOS ANGELES LAKERS v. CLEVELAND CAVALIERS | * | 34:15 | 19 | 8 / 13 | 7 / 12 | 1 / 1 | 2 / 3 | 5 | 1 | 5 | 0 | 0 | 4 | 2 | 28 |
| 2021-10-31 | 95 - 85 | LOS ANGELES LAKERS v. HOUSTON ROCKETS | * | 34:53 | 20 | 9 / 22 | 7 / 18 | 2 / 4 | 0 / 1 | 7 | 1 | 9 | 1 | 0 | 2 | 4 | 26 |
| 2021-11-02 | 119 - 117 | LOS ANGELES LAKERS v. HOUSTON ROCKETS | * | 37:11 | 27 | 10 / 21 | 10 / 17 | 0 / 4 | 7 / 8 | 4 | 5 | 7 | 0 | 0 | 3 | 1 | 34 |
| 2021-11-04 | 104 - 107 | LOS ANGELES LAKERS v. OKLAHOMA CITY THUNDER | * | 34:39 | 27 | 10 / 23 | 7 / 17 | 3 / 6 | 4 / 4 | 5 | 1 | 5 | 0 | 0 | 4 | 2 | 29 |
| 2021-11-06 | 105 - 90 | LOS ANGELES LAKERS @ PORTLAND TRAIL BLAZERS | * | 29:29 | 8 | 1 / 13 | 0 / 10 | 1 / 3 | 5 / 8 | 7 | 2 | 6 | 2 | 0 | 6 | 3 | 16 |
| 2021-11-12 | 83 - 107 | LOS ANGELES LAKERS v. MINNESOTA TIMBERWOLVES | * | 30:53 | 20 | 7 / 11 | 5 / 7 | 2 / 4 | 4 / 6 | 5 | 0 | 3 | 0 | 0 | 5 | 1 | 27 |
| 2021-11-14 | 114 - 106 | LOS ANGELES LAKERS v. SAN ANTONIO SPURS | * | 34:17 | 14 | 5 / 11 | 2 / 6 | 3 / 5 | 1 / 2 | 10 | 1 | 7 | 2 | 0 | 7 | 3 | 34 |
| 2021-11-15 | 103 - 121 | LOS ANGELES LAKERS v. CHICAGO BULLS | * | 31:15 | 25 | 8 / 19 | 8 / 13 | 0 / 6 | 9 / 10 | 6 | 0 | 8 | 1 | 0 | 4 | 3 | 32 |
| 2021-11-17 | 109 - 102 | LOS ANGELES LAKERS @ MILWAUKEE BUCKS | * | 35:38 | 19 | 7 / 16 | 5 / 11 | 2 / 5 | 3 / 4 | 3 | 1 | 15 | 1 | 0 | 3 | 3 | 32 |
| 2021-11-19 | 130 - 108 | LOS ANGELES LAKERS @ BOSTON CELTICS | * | 31:20 | 12 | 5 / 13 | 4 / 9 | 1 / 4 | 1 / 4 | 3 | 1 | 6 | 1 | 0 | 2 | 5 | 14 |
| 2021-11-21 | 116 - 121 | LOS ANGELES LAKERS @ DETROIT PISTONS | * | 34:49 | 26 | 10 / 21 | 9 / 15 | 1 / 6 | 5 / 8 | 8 | 1 | 10 | 2 | 0 | 3 | 4 | 36 |
| 2021-11-23 | 106 - 100 | LOS ANGELES LAKERS @ NEW YORK KNICKS | * | 37:09 | 31 | 10 / 18 | 7 / 12 | 3 / 6 | 8 / 9 | 12 | 1 | 10 | 2 | 0 | 6 | 2 | 53 |
| 2021-11-24 | 116 - 124 | LOS ANGELES LAKERS @ INDIANA PACERS | * | 39:31 | 20 | 5 / 15 | 4 / 12 | 1 / 3 | 9 / 11 | 6 | 1 | 5 | 0 | 1 | 4 | 3 | 23 |
| 2021-11-28 | 110 - 106 | LOS ANGELES LAKERS v. DETROIT PISTONS | * | 36:35 | 25 | 10 / 16 | 9 / 13 | 1 / 3 | 4 / 8 | 4 | 2 | 9 | 1 | 0 | 3 | 2 | 34 |
| 2021-11-30 | 92 - 117 | LOS ANGELES LAKERS @ SACRAMENTO KINGS | * | 34:42 | 23 | 9 / 21 | 8 / 16 | 1 / 5 | 4 / 7 | 5 | 0 | 6 | 1 | 0 | 4 | 2 | 24 |
| 2021-12-03 | 115 - 119 | LOS ANGELES LAKERS v. LOS ANGELES CLIPPERS | * | 36:15 | 10 | 4 / 8 | 2 / 6 | 2 / 2 | 0 / 0 | 1 | 1 | 9 | 1 | 0 | 2 | 4 | 20 |
| 2021-12-07 | 117 - 102 | LOS ANGELES LAKERS v. BOSTON CELTICS | * | 35:42 | 24 | 9 / 16 | 8 / 12 | 1 / 4 | 5 / 6 | 2 | 1 | 11 | 1 | 0 | 4 | 2 | 35 |
| 2021-12-09 | 108 - 95 | LOS ANGELES LAKERS @ MEMPHIS GRIZZLIES | * | 33:20 | 9 | 3 / 9 | 1 / 6 | 2 / 3 | 1 / 4 | 6 | 0 | 7 | 0 | 1 | 6 | 4 | 18 |
| 2021-12-10 | 95 - 116 | LOS ANGELES LAKERS @ OKLAHOMA CITY THUNDER | * | 33:20 | 8 | 4 / 8 | 4 / 7 | 0 / 1 | 0 / 0 | 7 | 2 | 7 | 0 | 1 | 5 | 1 | 24 |
| 2021-12-12 | 106 - 94 | LOS ANGELES LAKERS v. ORLANDO MAGIC | * | 35:28 | 19 | 9 / 18 | 9 / 18 | 0 / 0 | 1 / 2 | 5 | 2 | 5 | 2 | 0 | 5 | 2 | 28 |
| 2021-12-17 | 110 - 92 | LOS ANGELES LAKERS @ MINNESOTA TIMBERWOLVES | * | 28:32 | 14 | 4 / 7 | 4 / 6 | 0 / 1 | 6 / 11 | 4 | 0 | 3 | 0 | 1 | 1 | 3 | 13 |
| 2021-12-19 | 115 - 110 | LOS ANGELES LAKERS @ CHICAGO BULLS | * | 38:08 | 20 | 9 / 19 | 9 / 17 | 0 / 2 | 2 / 6 | 7 | 2 | 8 | 1 | 2 | 6 | 4 | 28 |
| 2021-12-21 | 90 - 108 | LOS ANGELES LAKERS v. PHOENIX SUNS | * | 36:32 | 22 | 10 / 20 | 10 / 18 | 0 / 2 | 2 / 4 | 9 | 1 | 5 | 3 | 0 | 7 | 3 | 35 |
| 2021-12-23 | 110 - 138 | LOS ANGELES LAKERS v. SAN ANTONIO SPURS | * | 35:07 | 30 | 12 / 20 | 11 / 18 | 1 / 2 | 5 / 9 | 7 | 0 | 4 | 1 | 0 | 5 | 3 | 35 |
| 2021-12-25 | 115 - 122 | LOS ANGELES LAKERS v. BROOKLYN NETS | * | 36:53 | 13 | 4 / 20 | 4 / 17 | 0 / 3 | 5 / 6 | 7 | 5 | 11 | 1 | 0 | 3 | 5 | 23 |
| 2021-12-28 | 123 - 132 | LOS ANGELES LAKERS @ HOUSTON ROCKETS | * | 34:45 | 24 | 10 / 17 | 8 / 15 | 2 / 2 | 2 / 6 | 9 | 4 | 10 | 2 | 0 | 7 | 1 | 45 |
| 2021-12-29 | 104 - 99 | LOS ANGELES LAKERS @ MEMPHIS GRIZZLIES | * | 39:33 | 16 | 7 / 16 | 5 / 12 | 2 / 4 | 0 / 0 | 8 | 2 | 12 | 0 | 0 | 5 | 5 | 34 |
| 2021-12-31 | 139 - 106 | LOS ANGELES LAKERS v. PORTLAND TRAIL BLAZERS | * | 30:27 | 15 | 5 / 10 | 5 / 7 | 0 / 3 | 5 / 6 | 13 | 0 | 12 | 2 | 0 | 4 | 2 | 40 |
| 2022-01-02 | 108 - 103 | LOS ANGELES LAKERS v. MINNESOTA TIMBERWOLVES | * | 33:24 | 20 | 7 / 16 | 7 / 11 | 0 / 5 | 6 / 8 | 3 | 0 | 5 | 1 | 1 | 9 | 5 | 26 |
| 2022-01-04 | 122 - 114 | LOS ANGELES LAKERS v. SACRAMENTO KINGS | * | 33:32 | 19 | 7 / 19 | 7 / 18 | 0 / 1 | 5 / 8 | 5 | 2 | 2 | 1 | 1 | 0 | 2 | 13 |
| 2022-01-07 | 134 - 118 | LOS ANGELES LAKERS v. ATLANTA HAWKS | * | 31:07 | 9 | 4 / 14 | 4 / 14 | 0 / 0 | 1 / 3 | 10 | 1 | 13 | 0 | 0 | 3 | 6 | 24 |
| 2022-01-09 | 119 - 127 | LOS ANGELES LAKERS v. MEMPHIS GRIZZLIES | * | 26:08 | 6 | 2 / 12 | 2 / 11 | 0 / 1 | 2 / 2 | 6 | 1 | 6 | 0 | 1 | 0 | 2 | 8 |
| 2022-01-12 | 125 - 116 | LOS ANGELES LAKERS @ SACRAMENTO KINGS | * | 37:18 | 8 | 2 / 14 | 2 / 9 | 0 / 5 | 4 / 5 | 9 | 3 | 6 | 1 | 0 | 1 | 3 | 15 |
| 2022-01-15 | 133 - 96 | LOS ANGELES LAKERS @ DENVER NUGGETS | * | 25:57 | 19 | 7 / 15 | 6 / 13 | 1 / 2 | 4 / 4 | 4 | 1 | 3 | 0 | 0 | 0 | 1 | 19 |
| 2022-01-17 | 101 - 95 | LOS ANGELES LAKERS v. UTAH JAZZ | * | 27:40 | 15 | 5 / 15 | 4 / 11 | 1 / 4 | 4 / 4 | 6 | 2 | 3 | 1 | 0 | 2 | 3 | 19 |
| 2022-01-19 | 104 - 111 | LOS ANGELES LAKERS v. INDIANA PACERS | * | 26:36 | 14 | 5 / 17 | 1 / 11 | 4 / 6 | 0 / 0 | 1 | 1 | 3 | 1 | 0 | 1 | 4 | 9 |
| 2022-01-21 | 105 - 116 | LOS ANGELES LAKERS @ ORLANDO MAGIC | * | 35:15 | 18 | 8 / 17 | 8 / 16 | 0 / 1 | 2 / 2 | 9 | 2 | 7 | 3 | 0 | 3 | 3 | 33 |
| 2022-01-23 | 113 - 107 | LOS ANGELES LAKERS @ MIAMI HEAT | * | 31:40 | 24 | 9 / 15 | 9 / 12 | 0 / 3 | 6 / 8 | 7 | 2 | 9 | 0 | 0 | 3 | 5 | 37 |
| 2022-01-25 | 96 - 106 | LOS ANGELES LAKERS @ BROOKLYN NETS | * | 32:44 | 15 | 7 / 14 | 7 / 12 | 0 / 2 | 1 / 1 | 6 | 0 | 4 | 1 | 0 | 5 | 3 | 24 |
| 2022-01-27 | 105 - 87 | LOS ANGELES LAKERS @ PHILADELPHIA 76ERS | * | 34:12 | 20 | 9 / 15 | 7 / 12 | 2 / 3 | 0 / 0 | 3 | 1 | 3 | 1 | 1 | 6 | 1 | 27 |
| 2022-01-28 | 117 - 114 | LOS ANGELES LAKERS @ CHARLOTTE HORNETS | * | 37:27 | 35 | 12 / 23 | 9 / 16 | 3 / 7 | 8 / 10 | 3 | 1 | 5 | 0 | 0 | 1 | 4 | 32 |
| 2022-01-30 | 129 - 121 | LOS ANGELES LAKERS @ ATLANTA HAWKS | * | 35:00 | 20 | 8 / 15 | 6 / 11 | 2 / 4 | 2 / 5 | 7 | 0 | 12 | 1 | 0 | 4 | 1 | 34 |
| 2022-02-02 | 99 - 94 | LOS ANGELES LAKERS v. PORTLAND TRAIL BLAZERS | * | 33:52 | 9 | 3 / 12 | 2 / 8 | 1 / 4 | 2 / 3 | 8 | 2 | 13 | 1 | 0 | 4 | 5 | 27 |
| 2022-02-03 | 111 - 110 | LOS ANGELES LAKERS @ LOS ANGELES CLIPPERS | * | 35:36 | 17 | 7 / 18 | 6 / 13 | 1 / 5 | 2 / 3 | 5 | 1 | 4 | 1 | 0 | 2 | 0 | 18 |
| 2022-02-05 | 122 - 115 | LOS ANGELES LAKERS v. NEW YORK KNICKS | * | 29:01 | 5 | 1 / 10 | 1 / 7 | 0 / 3 | 3 / 7 | 3 | 1 | 6 | 1 | 1 | 4 | 2 | 6 |
| 2022-02-08 | 116 - 131 | LOS ANGELES LAKERS v. MILWAUKEE BUCKS | * | 26:05 | 10 | 3 / 11 | 3 / 10 | 0 / 1 | 4 / 7 | 8 | 2 | 5 | 0 | 1 | 4 | 1 | 17 |