| 2021-10-22 | 112 - 123 | CLEVELAND CAVALIERS v. CHARLOTTE HORNETS | | 25:23 | 7 | 3 / 5 | 3 / 3 | 0 / 2 | 1 / 2 | 1 | 1 | 1 | 0 | 0 | 1 | 2 | 8 |
| 2021-10-23 | 101 - 95 | CLEVELAND CAVALIERS v. ATLANTA HAWKS | | 33:37 | 9 | 3 / 8 | 2 / 6 | 1 / 2 | 2 / 4 | 1 | 3 | 3 | 0 | 0 | 0 | 3 | 9 |
| 2021-10-25 | 87 - 99 | CLEVELAND CAVALIERS @ DENVER NUGGETS | | 28:29 | 4 | 2 / 5 | 2 / 5 | 0 / 0 | 0 / 0 | 1 | 1 | 2 | 2 | 2 | 1 | 2 | 6 |
| 2021-11-10 | 94 - 97 | CLEVELAND CAVALIERS v. WASHINGTON WIZARDS | * | 28:01 | 2 | 1 / 4 | 1 / 2 | 0 / 2 | 0 / 0 | 5 | 1 | 1 | 0 | 0 | 1 | 3 | 7 |
| 2021-11-12 | 98 - 78 | CLEVELAND CAVALIERS v. DETROIT PISTONS | * | 23:29 | 9 | 4 / 12 | 3 / 5 | 1 / 7 | 0 / 1 | 8 | 1 | 1 | 1 | 0 | 3 | 1 | 14 |
| 2021-11-13 | 91 - 89 | CLEVELAND CAVALIERS v. BOSTON CELTICS | * | 17:50 | 2 | 0 / 7 | 0 / 4 | 0 / 3 | 2 / 2 | 3 | 0 | 0 | 0 | 0 | 2 | 2 | 0 |
| 2021-11-15 | 92 - 98 | CLEVELAND CAVALIERS v. BOSTON CELTICS | * | 31:32 | 12 | 4 / 8 | 3 / 4 | 1 / 4 | 3 / 4 | 4 | 1 | 3 | 3 | 0 | 1 | 3 | 19 |
| 2021-11-17 | 109 - 99 | CLEVELAND CAVALIERS @ BROOKLYN NETS | * | 39:01 | 8 | 3 / 11 | 3 / 9 | 0 / 2 | 2 / 2 | 2 | 4 | 2 | 1 | 0 | 2 | 3 | 11 |
| 2021-11-22 | 112 - 117 | CLEVELAND CAVALIERS v. BROOKLYN NETS | * | 36:26 | 15 | 4 / 9 | 1 / 2 | 3 / 7 | 4 / 4 | 3 | 1 | 2 | 2 | 0 | 1 | 0 | 19 |
| 2021-11-24 | 115 - 120 | CLEVELAND CAVALIERS v. PHOENIX SUNS | * | 34:13 | 5 | 2 / 8 | 1 / 4 | 1 / 4 | 0 / 1 | 1 | 2 | 4 | 1 | 0 | 0 | 2 | 6 |
| 2021-11-27 | 105 - 92 | CLEVELAND CAVALIERS v. ORLANDO MAGIC | * | 26:42 | 7 | 3 / 9 | 2 / 6 | 1 / 3 | 0 / 0 | 4 | 1 | 1 | 0 | 0 | 2 | 4 | 9 |
| 2021-11-29 | 96 - 114 | CLEVELAND CAVALIERS @ DALLAS MAVERICKS | * | 26:30 | 10 | 4 / 6 | 3 / 4 | 1 / 2 | 1 / 1 | 1 | 0 | 2 | 0 | 1 | 0 | 3 | 10 |
| 2021-12-01 | 85 - 111 | CLEVELAND CAVALIERS @ MIAMI HEAT | * | 29:27 | 10 | 4 / 5 | 4 / 5 | 0 / 0 | 2 / 2 | 2 | 1 | 2 | 1 | 1 | 3 | 2 | 17 |
| 2021-12-03 | 101 - 116 | CLEVELAND CAVALIERS @ WASHINGTON WIZARDS | * | 29:03 | 8 | 1 / 4 | 0 / 2 | 1 / 2 | 5 / 6 | 3 | 1 | 2 | 0 | 0 | 1 | 2 | 11 |
| 2021-12-05 | 108 - 109 | CLEVELAND CAVALIERS v. UTAH JAZZ | * | 25:49 | 6 | 2 / 9 | 0 / 2 | 2 / 7 | 0 / 0 | 1 | 2 | 3 | 2 | 0 | 1 | 2 | 8 |
| 2021-12-06 | 112 - 104 | CLEVELAND CAVALIERS @ MILWAUKEE BUCKS | * | 18:15 | 0 | 0 / 6 | 0 / 3 | 0 / 3 | 0 / 0 | 2 | 1 | 0 | 2 | 0 | 0 | 2 | -1 |
| 2021-12-08 | 115 - 92 | CLEVELAND CAVALIERS v. CHICAGO BULLS | * | 27:43 | 9 | 4 / 7 | 4 / 6 | 0 / 1 | 1 / 2 | 2 | 2 | 1 | 0 | 0 | 1 | 4 | 11 |
| 2021-12-10 | 106 - 123 | CLEVELAND CAVALIERS @ MINNESOTA TIMBERWOLVES | * | 30:57 | 16 | 7 / 10 | 6 / 7 | 1 / 3 | 1 / 1 | 2 | 1 | 1 | 0 | 1 | 1 | 0 | 17 |
| 2021-12-11 | 117 - 103 | CLEVELAND CAVALIERS v. SACRAMENTO KINGS | * | 29:44 | 20 | 7 / 9 | 5 / 6 | 2 / 3 | 4 / 4 | 3 | 1 | 3 | 2 | 0 | 2 | 1 | 29 |
| 2021-12-13 | 105 - 94 | CLEVELAND CAVALIERS v. MIAMI HEAT | * | 35:00 | 18 | 7 / 12 | 3 / 4 | 4 / 8 | 0 / 0 | 5 | 0 | 2 | 0 | 0 | 1 | 3 | 21 |
| 2021-12-15 | 124 - 89 | CLEVELAND CAVALIERS v. HOUSTON ROCKETS | * | 21:34 | 20 | 7 / 9 | 4 / 6 | 3 / 3 | 3 / 4 | 2 | 1 | 0 | 1 | 0 | 1 | 3 | 22 |
| 2021-12-28 | 108 - 104 | CLEVELAND CAVALIERS @ NEW ORLEANS PELICANS | * | 30:35 | 6 | 2 / 6 | 2 / 5 | 0 / 1 | 2 / 4 | 0 | 2 | 3 | 1 | 0 | 3 | 5 | 9 |
| 2021-12-30 | 110 - 93 | CLEVELAND CAVALIERS @ WASHINGTON WIZARDS | * | 30:30 | 11 | 3 / 7 | 1 / 4 | 2 / 3 | 3 / 4 | 1 | 0 | 1 | 0 | 0 | 2 | 3 | 10 |
| 2021-12-31 | 118 - 121 | CLEVELAND CAVALIERS v. ATLANTA HAWKS | * | 30:36 | 10 | 4 / 4 | 3 / 3 | 1 / 1 | 1 / 3 | 2 | 0 | 5 | 0 | 0 | 1 | 6 | 16 |
| 2022-01-02 | 108 - 104 | CLEVELAND CAVALIERS v. INDIANA PACERS | * | 12:15 | 2 | 1 / 1 | 1 / 1 | 0 / 0 | 0 / 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 4 |
| 2022-01-14 | 109 - 114 | CLEVELAND CAVALIERS @ SAN ANTONIO SPURS | | 16:29 | 6 | 2 / 6 | 2 / 4 | 0 / 2 | 2 / 4 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 3 |
| 2022-01-15 | 102 - 107 | CLEVELAND CAVALIERS @ OKLAHOMA CITY THUNDER | | 24:29 | 7 | 1 / 5 | 1 / 2 | 0 / 3 | 5 / 6 | 0 | 0 | 1 | 0 | 1 | 0 | 4 | 2 |
| 2022-01-17 | 114 - 107 | CLEVELAND CAVALIERS v. BROOKLYN NETS | * | 32:14 | 15 | 5 / 7 | 4 / 5 | 1 / 2 | 4 / 4 | 1 | 0 | 0 | 2 | 0 | 0 | 2 | 16 |
| 2022-01-19 | 117 - 104 | CLEVELAND CAVALIERS @ CHICAGO BULLS | * | 29:30 | 8 | 3 / 7 | 3 / 6 | 0 / 1 | 2 / 3 | 0 | 0 | 3 | 0 | 0 | 1 | 4 | 7 |
| 2022-01-22 | 94 - 87 | CLEVELAND CAVALIERS v. OKLAHOMA CITY THUNDER | * | 35:07 | 8 | 3 / 6 | 3 / 3 | 0 / 3 | 2 / 2 | 4 | 1 | 1 | 3 | 1 | 5 | 4 | 18 |
| 2022-01-24 | 95 - 93 | CLEVELAND CAVALIERS v. NEW YORK KNICKS | * | 32:43 | 14 | 6 / 13 | 6 / 10 | 0 / 3 | 2 / 3 | 3 | 3 | 2 | 0 | 1 | 0 | 1 | 13 |
| 2022-01-26 | 115 - 99 | CLEVELAND CAVALIERS v. MILWAUKEE BUCKS | * | 28:55 | 3 | 1 / 3 | 0 / 0 | 1 / 3 | 0 / 0 | 2 | 0 | 3 | 1 | 1 | 0 | 3 | 6 |
| 2022-01-30 | 115 - 105 | CLEVELAND CAVALIERS @ DETROIT PISTONS | * | 33:21 | 9 | 4 / 7 | 3 / 4 | 1 / 3 | 0 / 0 | 2 | 1 | 4 | 1 | 0 | 1 | 2 | 15 |
| 2022-01-31 | 93 - 90 | CLEVELAND CAVALIERS v. NEW ORLEANS PELICANS | * | 25:29 | 14 | 4 / 5 | 2 / 3 | 2 / 2 | 4 / 4 | 1 | 2 | 1 | 0 | 0 | 1 | 2 | 18 |
| 2022-02-02 | 115 - 104 | CLEVELAND CAVALIERS @ HOUSTON ROCKETS | * | 32:01 | 11 | 5 / 7 | 4 / 6 | 1 / 1 | 0 / 0 | 2 | 0 | 1 | 1 | 1 | 0 | 3 | 12 |
| 2022-02-04 | 101 - 102 | CLEVELAND CAVALIERS @ CHARLOTTE HORNETS | * | 36:03 | 9 | 3 / 7 | 2 / 3 | 1 / 4 | 2 / 2 | 2 | 0 | 4 | 0 | 0 | 0 | 3 | 11 |
| 2022-02-06 | 98 - 85 | CLEVELAND CAVALIERS v. INDIANA PACERS | * | 28:05 | 2 | 1 / 7 | 1 / 5 | 0 / 2 | 0 / 0 | 1 | 2 | 0 | 1 | 0 | 0 | 4 | 0 |
| 2022-02-09 | 105 - 92 | CLEVELAND CAVALIERS v. SAN ANTONIO SPURS | * | 27:22 | 14 | 4 / 6 | 2 / 4 | 2 / 2 | 4 / 4 | 3 | 1 | 1 | 2 | 0 | 1 | 1 | 20 |
| 2022-02-11 | 113 - 120 | CLEVELAND CAVALIERS @ INDIANA PACERS | * | 33:09 | 10 | 2 / 7 | 2 / 5 | 0 / 2 | 6 / 6 | 1 | 0 | 3 | 0 | 2 | 1 | 3 | 8 |
| 2022-02-12 | 103 - 93 | CLEVELAND CAVALIERS @ PHILADELPHIA 76ERS | * | 31:36 | 5 | 1 / 1 | 1 / 1 | 0 / 0 | 3 / 4 | 1 | 1 | 1 | 0 | 0 | 1 | 3 | 8 |
| 2022-02-15 | 124 - 116 | CLEVELAND CAVALIERS @ ATLANTA HAWKS | * | 26:25 | 6 | 2 / 3 | 0 / 0 | 2 / 3 | 0 / 0 | 1 | 0 | 4 | 1 | 0 | 1 | 6 | 12 |
| 2022-02-24 | 106 - 103 | CLEVELAND CAVALIERS @ DETROIT PISTONS | * | 27:39 | 11 | 4 / 6 | 2 / 3 | 2 / 3 | 1 / 3 | 3 | 2 | 0 | 1 | 0 | 0 | 3 | 13 |
| 2022-02-26 | 92 - 86 | CLEVELAND CAVALIERS v. WASHINGTON WIZARDS | * | 37:28 | 6 | 3 / 7 | 3 / 7 | 0 / 0 | 0 / 0 | 2 | 2 | 3 | 2 | 0 | 1 | 2 | 12 |
| 2022-02-28 | 122 - 127 | CLEVELAND CAVALIERS v. MINNESOTA TIMBERWOLVES | * | 28:23 | 6 | 1 / 5 | 0 / 2 | 1 / 3 | 3 / 4 | 2 | 3 | 1 | 1 | 0 | 0 | 2 | 8 |
| 2022-03-02 | 98 - 119 | CLEVELAND CAVALIERS v. CHARLOTTE HORNETS | * | 28:15 | 4 | 2 / 6 | 2 / 4 | 0 / 2 | 0 / 0 | 1 | 0 | 0 | 1 | 0 | 0 | 3 | 2 |
| 2022-03-04 | 125 - 119 | CLEVELAND CAVALIERS @ PHILADELPHIA 76ERS | * | 29:15 | 22 | 7 / 8 | 7 / 7 | 0 / 1 | 8 / 9 | 2 | 1 | 3 | 0 | 0 | 3 | 2 | 29 |
| 2022-03-06 | 104 - 96 | CLEVELAND CAVALIERS v. TORONTO RAPTORS | * | 22:05 | 2 | 1 / 7 | 1 / 4 | 0 / 3 | 0 / 0 | 2 | 2 | 1 | 0 | 1 | 2 | 3 | 2 |
| 2022-03-08 | 124 - 127 | CLEVELAND CAVALIERS @ INDIANA PACERS | * | 33:13 | 11 | 4 / 7 | 3 / 6 | 1 / 1 | 2 / 2 | 0 | 1 | 1 | 2 | 0 | 1 | 2 | 13 |
| 2022-03-11 | 117 - 105 | CLEVELAND CAVALIERS @ MIAMI HEAT | * | 29:51 | 9 | 4 / 9 | 3 / 7 | 1 / 2 | 0 / 0 | 0 | 2 | 1 | 0 | 0 | 1 | 2 | 8 |
| 2022-03-12 | 101 - 91 | CLEVELAND CAVALIERS @ CHICAGO BULLS | * | 33:38 | 6 | 2 / 5 | 2 / 4 | 0 / 1 | 2 / 2 | 2 | 1 | 2 | 2 | 0 | 1 | 1 | 11 |