| 2021-10-22 | 112 - 123 | CLEVELAND CAVALIERS v. CHARLOTTE HORNETS | | 17:00 | 9 | 4 / 8 | 3 / 4 | 1 / 4 | 0 / 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 8 |
| 2021-10-23 | 101 - 95 | CLEVELAND CAVALIERS v. ATLANTA HAWKS | | 20:30 | 5 | 2 / 9 | 1 / 3 | 1 / 6 | 0 / 0 | 3 | 1 | 1 | 0 | 0 | 0 | 1 | 3 |
| 2021-10-25 | 87 - 99 | CLEVELAND CAVALIERS @ DENVER NUGGETS | | 11:28 | 0 | 0 / 1 | 0 / 0 | 0 / 1 | 0 / 0 | 2 | 0 | 1 | 0 | 0 | 1 | 2 | 3 |
| 2021-10-27 | 79 - 92 | CLEVELAND CAVALIERS @ LOS ANGELES CLIPPERS | | 4:21 | 0 | 0 / 0 | 0 / 0 | 0 / 0 | 0 / 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2021-10-30 | 101 - 92 | CLEVELAND CAVALIERS @ PHOENIX SUNS | | 30:07 | 20 | 7 / 15 | 1 / 3 | 6 / 12 | 0 / 0 | 2 | 1 | 2 | 2 | 0 | 3 | 3 | 22 |
| 2021-11-01 | 110 - 113 | CLEVELAND CAVALIERS @ CHARLOTTE HORNETS | | 20:59 | 13 | 4 / 5 | 0 / 0 | 4 / 5 | 1 / 2 | 0 | 0 | 2 | 0 | 0 | 0 | 3 | 13 |
| 2021-11-03 | 107 - 104 | CLEVELAND CAVALIERS v. PORTLAND TRAIL BLAZERS | | 17:00 | 12 | 4 / 7 | 0 / 0 | 4 / 7 | 0 / 0 | 3 | 0 | 1 | 0 | 0 | 1 | 0 | 14 |
| 2021-11-05 | 101 - 102 | CLEVELAND CAVALIERS @ TORONTO RAPTORS | | 26:01 | 17 | 5 / 12 | 0 / 2 | 5 / 10 | 2 / 4 | 2 | 0 | 2 | 0 | 1 | 1 | 1 | 12 |
| 2021-11-07 | 109 - 126 | CLEVELAND CAVALIERS @ NEW YORK KNICKS | | 31:03 | 2 | 0 / 5 | 0 / 0 | 0 / 5 | 2 / 2 | 4 | 1 | 2 | 0 | 1 | 3 | 3 | 6 |
| 2021-11-10 | 94 - 97 | CLEVELAND CAVALIERS v. WASHINGTON WIZARDS | | 28:33 | 9 | 3 / 6 | 2 / 2 | 1 / 4 | 2 / 3 | 6 | 0 | 1 | 2 | 0 | 0 | 3 | 14 |
| 2021-11-12 | 98 - 78 | CLEVELAND CAVALIERS v. DETROIT PISTONS | | 22:46 | 17 | 7 / 13 | 6 / 7 | 1 / 6 | 2 / 2 | 2 | 0 | 1 | 1 | 0 | 1 | 2 | 16 |
| 2021-11-13 | 91 - 89 | CLEVELAND CAVALIERS v. BOSTON CELTICS | | 29:17 | 9 | 3 / 9 | 1 / 3 | 2 / 6 | 1 / 2 | 3 | 1 | 1 | 2 | 1 | 1 | 2 | 9 |
| 2021-11-15 | 92 - 98 | CLEVELAND CAVALIERS v. BOSTON CELTICS | | 31:19 | 26 | 10 / 17 | 4 / 5 | 6 / 12 | 0 / 0 | 2 | 0 | 5 | 2 | 0 | 0 | 2 | 28 |
| 2021-11-17 | 109 - 99 | CLEVELAND CAVALIERS @ BROOKLYN NETS | | 19:16 | 11 | 3 / 8 | 1 / 2 | 2 / 6 | 3 / 4 | 3 | 1 | 1 | 1 | 0 | 0 | 2 | 11 |
| 2021-11-24 | 115 - 120 | CLEVELAND CAVALIERS v. PHOENIX SUNS | | 28:26 | 23 | 9 / 15 | 4 / 8 | 5 / 7 | 0 / 0 | 4 | 0 | 2 | 1 | 0 | 1 | 3 | 25 |
| 2021-11-27 | 105 - 92 | CLEVELAND CAVALIERS v. ORLANDO MAGIC | | 22:29 | 10 | 3 / 11 | 1 / 5 | 2 / 6 | 2 / 2 | 6 | 0 | 1 | 1 | 1 | 0 | 1 | 9 |
| 2021-12-05 | 108 - 109 | CLEVELAND CAVALIERS v. UTAH JAZZ | | 20:43 | 11 | 4 / 7 | 2 / 2 | 2 / 5 | 1 / 2 | 5 | 0 | 4 | 2 | 0 | 3 | 1 | 21 |
| 2021-12-06 | 112 - 104 | CLEVELAND CAVALIERS @ MILWAUKEE BUCKS | | 25:14 | 9 | 3 / 11 | 2 / 3 | 1 / 8 | 2 / 2 | 0 | 0 | 2 | 3 | 1 | 0 | 1 | 5 |
| 2021-12-08 | 115 - 92 | CLEVELAND CAVALIERS v. CHICAGO BULLS | | 21:50 | 6 | 2 / 4 | 0 / 1 | 2 / 3 | 0 / 0 | 1 | 0 | 1 | 3 | 2 | 2 | 3 | 9 |
| 2021-12-10 | 106 - 123 | CLEVELAND CAVALIERS @ MINNESOTA TIMBERWOLVES | | 27:42 | 13 | 5 / 10 | 4 / 7 | 1 / 3 | 2 / 2 | 0 | 1 | 4 | 3 | 0 | 1 | 4 | 17 |
| 2021-12-11 | 117 - 103 | CLEVELAND CAVALIERS v. SACRAMENTO KINGS | | 27:25 | 18 | 6 / 16 | 2 / 6 | 4 / 10 | 2 / 3 | 1 | 1 | 2 | 1 | 1 | 0 | 3 | 11 |
| 2021-12-13 | 105 - 94 | CLEVELAND CAVALIERS v. MIAMI HEAT | | 6:07 | 0 | 0 / 3 | 0 / 2 | 0 / 1 | 0 / 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | -2 |
| 2021-12-15 | 124 - 89 | CLEVELAND CAVALIERS v. HOUSTON ROCKETS | | 18:01 | 8 | 3 / 8 | 2 / 3 | 1 / 5 | 1 / 4 | 1 | 0 | 1 | 1 | 0 | 3 | 4 | 6 |
| 2021-12-18 | 90 - 119 | CLEVELAND CAVALIERS @ MILWAUKEE BUCKS | | 27:05 | 23 | 8 / 12 | 3 / 3 | 5 / 9 | 2 / 2 | 2 | 3 | 4 | 1 | 0 | 1 | 1 | 30 |
| 2021-12-22 | 111 - 101 | CLEVELAND CAVALIERS @ BOSTON CELTICS | | 30:59 | 13 | 5 / 14 | 4 / 7 | 1 / 7 | 2 / 2 | 6 | 0 | 1 | 1 | 0 | 1 | 3 | 13 |
| 2022-01-07 | 101 - 114 | CLEVELAND CAVALIERS @ PORTLAND TRAIL BLAZERS | | 30:29 | 14 | 5 / 9 | 1 / 2 | 4 / 7 | 0 / 0 | 3 | 0 | 0 | 1 | 0 | 0 | 2 | 14 |
| 2022-01-09 | 96 - 82 | CLEVELAND CAVALIERS @ GOLDEN STATE WARRIORS | | 19:49 | 4 | 1 / 6 | 1 / 4 | 0 / 2 | 2 / 4 | 1 | 1 | 3 | 2 | 0 | 0 | 0 | 4 |
| 2022-01-10 | 108 - 109 | CLEVELAND CAVALIERS @ SACRAMENTO KINGS | | 30:53 | 15 | 5 / 9 | 3 / 3 | 2 / 6 | 3 / 4 | 3 | 0 | 1 | 0 | 0 | 1 | 2 | 15 |
| 2022-01-12 | 91 - 111 | CLEVELAND CAVALIERS @ UTAH JAZZ | | 30:40 | 8 | 3 / 12 | 2 / 5 | 1 / 7 | 1 / 2 | 1 | 0 | 0 | 2 | 0 | 0 | 4 | 1 |
| 2022-01-14 | 109 - 114 | CLEVELAND CAVALIERS @ SAN ANTONIO SPURS | | 23:51 | 14 | 5 / 12 | 3 / 7 | 2 / 5 | 2 / 5 | 0 | 2 | 2 | 1 | 0 | 1 | 2 | 10 |
| 2022-01-15 | 102 - 107 | CLEVELAND CAVALIERS @ OKLAHOMA CITY THUNDER | | 12:58 | 2 | 1 / 4 | 1 / 2 | 0 / 2 | 0 / 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 |
| 2022-01-17 | 114 - 107 | CLEVELAND CAVALIERS v. BROOKLYN NETS | | 24:04 | 7 | 3 / 10 | 3 / 4 | 0 / 6 | 1 / 2 | 3 | 1 | 3 | 0 | 0 | 1 | 2 | 7 |
| 2022-01-19 | 117 - 104 | CLEVELAND CAVALIERS @ CHICAGO BULLS | | 16:53 | 2 | 1 / 5 | 1 / 1 | 0 / 4 | 0 / 0 | 1 | 0 | 1 | 1 | 0 | 2 | 2 | 3 |
| 2022-01-22 | 94 - 87 | CLEVELAND CAVALIERS v. OKLAHOMA CITY THUNDER | | 18:48 | 10 | 3 / 7 | 2 / 2 | 1 / 5 | 3 / 5 | 1 | 0 | 1 | 0 | 0 | 0 | 3 | 6 |
| 2022-01-24 | 95 - 93 | CLEVELAND CAVALIERS v. NEW YORK KNICKS | | 10:44 | 0 | 0 / 5 | 0 / 2 | 0 / 3 | 0 / 0 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | -2 |
| 2022-01-26 | 115 - 99 | CLEVELAND CAVALIERS v. MILWAUKEE BUCKS | | 34:09 | 23 | 8 / 17 | 2 / 3 | 6 / 14 | 1 / 1 | 2 | 1 | 4 | 2 | 0 | 2 | 2 | 25 |
| 2022-01-30 | 115 - 105 | CLEVELAND CAVALIERS @ DETROIT PISTONS | | 22:26 | 13 | 4 / 7 | 2 / 3 | 2 / 4 | 3 / 5 | 0 | 1 | 1 | 1 | 0 | 1 | 4 | 12 |
| 2022-01-31 | 93 - 90 | CLEVELAND CAVALIERS v. NEW ORLEANS PELICANS | * | 37:57 | 7 | 3 / 16 | 3 / 9 | 0 / 7 | 1 / 1 | 2 | 0 | 12 | 0 | 0 | 1 | 4 | 9 |
| 2022-02-02 | 115 - 104 | CLEVELAND CAVALIERS @ HOUSTON ROCKETS | * | 35:27 | 13 | 5 / 12 | 2 / 6 | 3 / 6 | 0 / 3 | 1 | 0 | 1 | 1 | 0 | 3 | 4 | 9 |
| 2022-02-04 | 101 - 102 | CLEVELAND CAVALIERS @ CHARLOTTE HORNETS | * | 15:27 | 5 | 2 / 8 | 1 / 4 | 1 / 4 | 0 / 0 | 1 | 0 | 1 | 0 | 0 | 0 | 2 | 1 |
| 2022-02-06 | 98 - 85 | CLEVELAND CAVALIERS v. INDIANA PACERS | | 30:41 | 22 | 8 / 16 | 4 / 6 | 4 / 10 | 2 / 2 | 3 | 1 | 5 | 1 | 0 | 0 | 2 | 24 |
| 2022-02-09 | 105 - 92 | CLEVELAND CAVALIERS v. SAN ANTONIO SPURS | | 19:33 | 8 | 2 / 4 | 0 / 1 | 2 / 3 | 2 / 4 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 6 |
| 2022-02-11 | 113 - 120 | CLEVELAND CAVALIERS @ INDIANA PACERS | | 19:56 | 14 | 6 / 12 | 5 / 8 | 1 / 4 | 1 / 2 | 0 | 0 | 2 | 1 | 0 | 2 | 1 | 12 |
| 2022-02-12 | 103 - 93 | CLEVELAND CAVALIERS @ PHILADELPHIA 76ERS | | 25:01 | 12 | 3 / 9 | 1 / 3 | 2 / 6 | 4 / 5 | 3 | 0 | 4 | 0 | 0 | 1 | 1 | 13 |
| 2022-02-15 | 124 - 116 | CLEVELAND CAVALIERS @ ATLANTA HAWKS | | 14:24 | 6 | 2 / 5 | 0 / 0 | 2 / 5 | 0 / 0 | 1 | 1 | 0 | 0 | 0 | 2 | 2 | 7 |
| 2022-02-24 | 106 - 103 | CLEVELAND CAVALIERS @ DETROIT PISTONS | | 19:59 | 9 | 2 / 7 | 0 / 3 | 2 / 4 | 3 / 4 | 1 | 0 | 2 | 0 | 0 | 1 | 2 | 7 |
| 2022-02-26 | 92 - 86 | CLEVELAND CAVALIERS v. WASHINGTON WIZARDS | | 28:51 | 19 | 7 / 13 | 5 / 8 | 2 / 5 | 3 / 5 | 4 | 0 | 5 | 1 | 0 | 3 | 1 | 24 |
| 2022-02-28 | 122 - 127 | CLEVELAND CAVALIERS v. MINNESOTA TIMBERWOLVES | | 28:26 | 21 | 5 / 9 | 0 / 0 | 5 / 9 | 6 / 8 | 1 | 0 | 5 | 1 | 0 | 3 | 3 | 25 |
| 2022-03-02 | 98 - 119 | CLEVELAND CAVALIERS v. CHARLOTTE HORNETS | | 19:44 | 9 | 3 / 6 | 1 / 1 | 2 / 5 | 1 / 2 | 1 | 0 | 4 | 0 | 0 | 2 | 2 | 12 |
| 2022-03-04 | 125 - 119 | CLEVELAND CAVALIERS @ PHILADELPHIA 76ERS | | 31:58 | 20 | 7 / 13 | 4 / 5 | 3 / 8 | 3 / 3 | 0 | 0 | 1 | 1 | 0 | 1 | 2 | 17 |
