| 2020-12-26 | 119 - 128 | CLEVELAND CAVALIERS @ DETROIT PISTONS | * | 37:33 | 15 | 4 / 12 | 1 / 4 | 3 / 8 | 4 / 5 | 8 | 1 | 3 | 0 | 0 | 3 | 1 | 21 |
| 2020-12-27 | 118 - 94 | CLEVELAND CAVALIERS v. PHILADELPHIA 76ERS | * | 8:50 | 4 | 2 / 6 | 2 / 5 | 0 / 1 | 0 / 0 | 2 | 1 | 2 | 1 | 0 | 0 | 0 | 6 |
| 2021-03-12 | 116 - 82 | CLEVELAND CAVALIERS @ NEW ORLEANS PELICANS | * | 10:01 | 4 | 1 / 4 | 0 / 1 | 1 / 3 | 1 / 2 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 1 |
| 2021-03-14 | 100 - 82 | CLEVELAND CAVALIERS @ ATLANTA HAWKS | * | 1:41 | 0 | 0 / 0 | 0 / 0 | 0 / 0 | 0 / 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2021-04-01 | 94 - 114 | CLEVELAND CAVALIERS v. PHILADELPHIA 76ERS | * | 20:10 | 13 | 4 / 10 | 1 / 4 | 3 / 6 | 2 / 2 | 3 | 1 | 3 | 0 | 0 | 3 | 1 | 17 |
| 2021-04-03 | 115 - 101 | CLEVELAND CAVALIERS @ MIAMI HEAT | * | 23:00 | 10 | 3 / 9 | 1 / 1 | 2 / 8 | 2 / 2 | 10 | 0 | 3 | 0 | 1 | 3 | 2 | 19 |
| 2021-04-05 | 101 - 125 | CLEVELAND CAVALIERS @ SAN ANTONIO SPURS | * | 26:19 | 9 | 4 / 8 | 3 / 5 | 1 / 3 | 0 / 0 | 7 | 1 | 3 | 2 | 0 | 2 | 3 | 20 |
| 2021-04-08 | 102 - 129 | CLEVELAND CAVALIERS @ OKLAHOMA CITY THUNDER | * | 23:18 | 18 | 6 / 12 | 3 / 4 | 3 / 8 | 3 / 4 | 10 | 1 | 2 | 2 | 0 | 2 | 1 | 28 |
| 2021-04-10 | 115 - 135 | CLEVELAND CAVALIERS v. TORONTO RAPTORS | * | 20:53 | 18 | 4 / 9 | 0 / 1 | 4 / 8 | 6 / 8 | 3 | 0 | 1 | 1 | 0 | 1 | 2 | 17 |
| 2021-04-11 | 109 - 116 | CLEVELAND CAVALIERS v. NEW ORLEANS PELICANS | * | 31:07 | 19 | 6 / 17 | 1 / 3 | 5 / 14 | 2 / 3 | 4 | 1 | 3 | 0 | 1 | 1 | 0 | 15 |
| 2021-04-14 | 90 - 103 | CLEVELAND CAVALIERS @ CHARLOTTE HORNETS | * | 26:41 | 17 | 6 / 12 | 4 / 7 | 2 / 5 | 3 / 3 | 7 | 4 | 4 | 0 | 0 | 0 | 2 | 26 |
| 2021-04-15 | 101 - 119 | CLEVELAND CAVALIERS v. GOLDEN STATE WARRIORS | * | 21:47 | 5 | 2 / 10 | 1 / 3 | 1 / 7 | 0 / 0 | 6 | 0 | 2 | 1 | 0 | 1 | 0 | 7 |
| 2021-04-17 | 106 - 96 | CLEVELAND CAVALIERS @ CHICAGO BULLS | * | 30:06 | 14 | 6 / 15 | 4 / 5 | 2 / 10 | 0 / 0 | 11 | 0 | 0 | 1 | 0 | 1 | 0 | 18 |
| 2021-04-19 | 109 - 105 | CLEVELAND CAVALIERS @ DETROIT PISTONS | * | 29:58 | 15 | 7 / 13 | 7 / 9 | 0 / 4 | 1 / 2 | 8 | 0 | 4 | 0 | 0 | 0 | 0 | 20 |
| 2021-04-21 | 121 - 105 | CLEVELAND CAVALIERS v. CHICAGO BULLS | * | 25:42 | 15 | 5 / 12 | 1 / 2 | 4 / 10 | 1 / 2 | 8 | 1 | 4 | 0 | 0 | 3 | 0 | 23 |
| 2021-04-23 | 108 - 102 | CLEVELAND CAVALIERS @ CHARLOTTE HORNETS | * | 27:19 | 12 | 3 / 11 | 0 / 4 | 3 / 7 | 3 / 3 | 4 | 1 | 2 | 0 | 0 | 1 | 1 | 12 |
| 2021-04-25 | 119 - 110 | CLEVELAND CAVALIERS @ WASHINGTON WIZARDS | * | 27:31 | 12 | 5 / 9 | 3 / 6 | 2 / 3 | 0 / 0 | 5 | 0 | 1 | 1 | 0 | 2 | 0 | 17 |
| 2021-04-26 | 112 - 96 | CLEVELAND CAVALIERS @ TORONTO RAPTORS | * | 24:02 | 11 | 3 / 9 | 3 / 5 | 0 / 4 | 5 / 5 | 7 | 0 | 4 | 0 | 0 | 2 | 3 | 18 |
| 2021-04-28 | 104 - 109 | CLEVELAND CAVALIERS v. ORLANDO MAGIC | * | 35:00 | 6 | 2 / 11 | 0 / 1 | 2 / 10 | 0 / 0 | 10 | 0 | 6 | 3 | 0 | 1 | 1 | 17 |
| 2021-04-30 | 93 - 122 | CLEVELAND CAVALIERS v. WASHINGTON WIZARDS | * | 22:08 | 0 | 0 / 0 | 0 / 0 | 0 / 0 | 0 / 0 | 10 | 0 | 1 | 0 | 0 | 3 | 2 | 14 |
| 2021-05-01 | 107 - 124 | CLEVELAND CAVALIERS v. MIAMI HEAT | * | 29:06 | 25 | 9 / 14 | 2 / 4 | 7 / 10 | 0 / 0 | 6 | 0 | 3 | 0 | 0 | 3 | 2 | 32 |
| 2021-05-04 | 118 - 134 | CLEVELAND CAVALIERS v. PHOENIX SUNS | * | 33:39 | 7 | 2 / 10 | 1 / 6 | 1 / 4 | 2 / 2 | 10 | 1 | 4 | 0 | 0 | 2 | 0 | 16 |
| 2021-05-05 | 105 - 141 | CLEVELAND CAVALIERS v. PORTLAND TRAIL BLAZERS | * | 25:52 | 18 | 7 / 14 | 3 / 4 | 4 / 10 | 0 / 0 | 6 | 2 | 2 | 1 | 0 | 0 | 1 | 22 |
| 2021-05-09 | 97 - 124 | CLEVELAND CAVALIERS v. DALLAS MAVERICKS | * | 26:54 | 8 | 2 / 9 | 1 / 5 | 1 / 4 | 3 / 4 | 9 | 2 | 3 | 1 | 0 | 1 | 1 | 16 |
| 2021-05-12 | 102 - 94 | CLEVELAND CAVALIERS v. BOSTON CELTICS | * | 33:36 | 30 | 10 / 16 | 4 / 7 | 6 / 9 | 4 / 4 | 14 | 0 | 3 | 2 | 0 | 3 | 1 | 46 |