| 2020-12-27 | 118 - 94 | CLEVELAND CAVALIERS v. PHILADELPHIA 76ERS | * | 29:20 | 22 | 8 / 15 | 7 / 13 | 1 / 2 | 5 / 6 | 3 | 0 | 3 | 1 | 0 | 1 | 1 | 22 |
| 2020-12-31 | 119 - 99 | CLEVELAND CAVALIERS @ INDIANA PACERS | * | 36:36 | 28 | 12 / 19 | 10 / 17 | 2 / 2 | 2 / 2 | 1 | 0 | 4 | 1 | 1 | 2 | 2 | 28 |
| 2021-01-02 | 91 - 96 | CLEVELAND CAVALIERS @ ATLANTA HAWKS | * | 35:54 | 27 | 10 / 18 | 8 / 13 | 2 / 5 | 5 / 5 | 1 | 1 | 3 | 3 | 0 | 0 | 3 | 27 |
| 2021-01-04 | 103 - 83 | CLEVELAND CAVALIERS @ ORLANDO MAGIC | * | 38:51 | 24 | 10 / 19 | 8 / 15 | 2 / 4 | 2 / 2 | 1 | 1 | 2 | 1 | 0 | 6 | 5 | 26 |
| 2021-01-06 | 105 - 94 | CLEVELAND CAVALIERS @ ORLANDO MAGIC | * | 35:00 | 21 | 8 / 20 | 5 / 13 | 3 / 7 | 2 / 2 | 2 | 1 | 4 | 1 | 1 | 0 | 1 | 16 |
| 2021-01-20 | 147 - 135 | CLEVELAND CAVALIERS v. BROOKLYN NETS | * | 38:12 | 42 | 16 / 29 | 11 / 18 | 5 / 11 | 5 / 9 | 2 | 3 | 5 | 2 | 1 | 1 | 5 | 37 |
| 2021-01-22 | 125 - 113 | CLEVELAND CAVALIERS v. BROOKLYN NETS | * | 29:34 | 25 | 8 / 19 | 7 / 14 | 1 / 5 | 8 / 9 | 1 | 1 | 9 | 0 | 0 | 1 | 5 | 25 |
| 2021-01-24 | 141 - 103 | CLEVELAND CAVALIERS @ BOSTON CELTICS | * | 16:11 | 13 | 3 / 8 | 3 / 7 | 0 / 1 | 7 / 7 | 1 | 1 | 2 | 0 | 0 | 6 | 2 | 18 |
| 2021-01-25 | 108 - 115 | CLEVELAND CAVALIERS v. LOS ANGELES LAKERS | * | 29:36 | 17 | 6 / 17 | 4 / 13 | 2 / 4 | 3 / 4 | 4 | 0 | 6 | 1 | 0 | 4 | 5 | 20 |
| 2021-01-27 | 122 - 107 | CLEVELAND CAVALIERS v. DETROIT PISTONS | * | 34:46 | 29 | 10 / 14 | 9 / 13 | 1 / 1 | 8 / 10 | 5 | 0 | 5 | 2 | 0 | 5 | 2 | 40 |
| 2021-01-29 | 102 - 81 | CLEVELAND CAVALIERS @ NEW YORK KNICKS | * | 34:54 | 17 | 6 / 18 | 6 / 14 | 0 / 4 | 5 / 6 | 0 | 1 | 5 | 0 | 0 | 2 | 2 | 12 |
| 2021-01-31 | 109 - 104 | CLEVELAND CAVALIERS @ MINNESOTA TIMBERWOLVES | * | 31:47 | 16 | 8 / 16 | 8 / 15 | 0 / 1 | 0 / 0 | 2 | 0 | 2 | 0 | 0 | 5 | 2 | 17 |
| 2021-02-03 | 99 - 121 | CLEVELAND CAVALIERS v. LOS ANGELES CLIPPERS | * | 38:28 | 27 | 11 / 21 | 10 / 20 | 1 / 1 | 4 / 4 | 1 | 0 | 5 | 1 | 0 | 1 | 1 | 25 |
| 2021-02-05 | 105 - 123 | CLEVELAND CAVALIERS v. MILWAUKEE BUCKS | * | 37:50 | 19 | 7 / 17 | 6 / 14 | 1 / 3 | 4 / 5 | 1 | 1 | 4 | 1 | 1 | 1 | 4 | 15 |
| 2021-02-06 | 99 - 124 | CLEVELAND CAVALIERS v. MILWAUKEE BUCKS | * | 34:19 | 17 | 6 / 18 | 4 / 12 | 2 / 6 | 3 / 6 | 2 | 1 | 3 | 1 | 0 | 3 | 2 | 12 |
| 2021-02-08 | 119 - 113 | CLEVELAND CAVALIERS @ PHOENIX SUNS | * | 34:13 | 23 | 10 / 15 | 8 / 11 | 2 / 4 | 1 / 1 | 2 | 0 | 5 | 0 | 0 | 2 | 4 | 27 |
| 2021-02-10 | 133 - 95 | CLEVELAND CAVALIERS @ DENVER NUGGETS | * | 28:54 | 4 | 1 / 9 | 1 / 7 | 0 / 2 | 2 / 3 | 2 | 1 | 8 | 1 | 0 | 3 | 2 | 10 |
| 2021-02-14 | 128 - 111 | CLEVELAND CAVALIERS @ LOS ANGELES CLIPPERS | * | 35:24 | 22 | 8 / 16 | 8 / 15 | 0 / 1 | 6 / 9 | 1 | 2 | 2 | 1 | 0 | 2 | 5 | 19 |
| 2021-02-19 | 103 - 120 | CLEVELAND CAVALIERS v. DENVER NUGGETS | * | 37:49 | 23 | 8 / 17 | 5 / 10 | 3 / 7 | 4 / 6 | 0 | 0 | 4 | 0 | 0 | 5 | 2 | 21 |
| 2021-02-23 | 112 - 111 | CLEVELAND CAVALIERS v. ATLANTA HAWKS | * | 33:50 | 29 | 9 / 16 | 6 / 11 | 3 / 5 | 8 / 10 | 1 | 0 | 5 | 1 | 0 | 6 | 5 | 33 |
| 2021-02-24 | 112 - 96 | CLEVELAND CAVALIERS v. HOUSTON ROCKETS | * | 38:56 | 23 | 9 / 19 | 6 / 11 | 3 / 8 | 2 / 2 | 1 | 1 | 3 | 1 | 0 | 1 | 0 | 20 |
| 2021-03-12 | 116 - 82 | CLEVELAND CAVALIERS @ NEW ORLEANS PELICANS | * | 31:18 | 19 | 7 / 18 | 7 / 15 | 0 / 3 | 5 / 5 | 2 | 0 | 1 | 3 | 0 | 0 | 2 | 14 |
| 2021-03-14 | 100 - 82 | CLEVELAND CAVALIERS @ ATLANTA HAWKS | * | 28:30 | 15 | 5 / 17 | 4 / 12 | 1 / 5 | 4 / 6 | 1 | 1 | 1 | 0 | 0 | 3 | 1 | 7 |
| 2021-03-16 | 113 - 98 | CLEVELAND CAVALIERS @ MIAMI HEAT | * | 33:32 | 21 | 7 / 17 | 5 / 9 | 2 / 8 | 5 / 6 | 0 | 1 | 3 | 1 | 0 | 1 | 5 | 16 |
| 2021-03-17 | 117 - 110 | CLEVELAND CAVALIERS v. BOSTON CELTICS | * | 36:34 | 29 | 10 / 20 | 8 / 15 | 2 / 5 | 7 / 7 | 6 | 1 | 6 | 0 | 0 | 4 | 2 | 36 |
| 2021-03-19 | 110 - 116 | CLEVELAND CAVALIERS v. SAN ANTONIO SPURS | * | 38:46 | 29 | 12 / 25 | 9 / 19 | 3 / 6 | 2 / 3 | 3 | 2 | 2 | 0 | 0 | 1 | 4 | 23 |
| 2021-03-21 | 116 - 105 | CLEVELAND CAVALIERS v. TORONTO RAPTORS | * | 38:45 | 36 | 13 / 24 | 7 / 15 | 6 / 9 | 4 / 6 | 2 | 1 | 4 | 2 | 0 | 6 | 1 | 38 |
| 2021-03-22 | 105 - 119 | CLEVELAND CAVALIERS v. SACRAMENTO KINGS | * | 28:43 | 15 | 6 / 15 | 6 / 12 | 0 / 3 | 3 / 3 | 4 | 0 | 7 | 0 | 0 | 2 | 1 | 19 |
| 2021-03-29 | 114 - 75 | CLEVELAND CAVALIERS @ UTAH JAZZ | * | 35:21 | 20 | 8 / 18 | 8 / 13 | 0 / 5 | 4 / 5 | 2 | 1 | 2 | 2 | 0 | 1 | 1 | 17 |
| 2021-04-01 | 94 - 114 | CLEVELAND CAVALIERS v. PHILADELPHIA 76ERS | * | 33:29 | 24 | 7 / 15 | 6 / 11 | 1 / 4 | 9 / 9 | 2 | 1 | 3 | 2 | 0 | 3 | 3 | 27 |
| 2021-04-03 | 115 - 101 | CLEVELAND CAVALIERS @ MIAMI HEAT | * | 35:19 | 26 | 11 / 17 | 11 / 13 | 0 / 4 | 4 / 4 | 3 | 0 | 3 | 3 | 0 | 5 | 3 | 34 |
| 2021-04-05 | 101 - 125 | CLEVELAND CAVALIERS @ SAN ANTONIO SPURS | * | 33:59 | 22 | 7 / 17 | 6 / 12 | 1 / 5 | 7 / 8 | 2 | 1 | 5 | 0 | 0 | 0 | 2 | 19 |
| 2021-04-08 | 102 - 129 | CLEVELAND CAVALIERS @ OKLAHOMA CITY THUNDER | * | 33:18 | 27 | 9 / 17 | 9 / 16 | 0 / 1 | 9 / 10 | 2 | 1 | 4 | 1 | 0 | 0 | 0 | 26 |
| 2021-04-10 | 115 - 135 | CLEVELAND CAVALIERS v. TORONTO RAPTORS | * | 35:22 | 29 | 10 / 20 | 9 / 17 | 1 / 3 | 8 / 9 | 0 | 0 | 5 | 0 | 0 | 2 | 2 | 25 |
| 2021-04-15 | 101 - 119 | CLEVELAND CAVALIERS v. GOLDEN STATE WARRIORS | * | 34:20 | 30 | 10 / 19 | 7 / 14 | 3 / 5 | 7 / 10 | 2 | 2 | 2 | 0 | 0 | 0 | 4 | 24 |
| 2021-04-17 | 106 - 96 | CLEVELAND CAVALIERS @ CHICAGO BULLS | * | 34:43 | 22 | 8 / 20 | 5 / 14 | 3 / 6 | 3 / 4 | 3 | 2 | 2 | 0 | 1 | 5 | 2 | 20 |
| 2021-04-19 | 109 - 105 | CLEVELAND CAVALIERS @ DETROIT PISTONS | * | 38:22 | 28 | 12 / 20 | 11 / 19 | 1 / 1 | 3 / 3 | 4 | 3 | 4 | 1 | 2 | 2 | 3 | 32 |
| 2021-04-21 | 121 - 105 | CLEVELAND CAVALIERS v. CHICAGO BULLS | * | 31:21 | 30 | 11 / 17 | 8 / 12 | 3 / 5 | 5 / 6 | 1 | 2 | 7 | 1 | 0 | 2 | 3 | 36 |
| 2021-04-23 | 108 - 102 | CLEVELAND CAVALIERS @ CHARLOTTE HORNETS | * | 34:20 | 28 | 11 / 19 | 8 / 11 | 3 / 8 | 3 / 5 | 6 | 1 | 2 | 1 | 0 | 4 | 5 | 32 |
| 2021-04-30 | 93 - 122 | CLEVELAND CAVALIERS v. WASHINGTON WIZARDS | * | 31:55 | 22 | 7 / 19 | 6 / 13 | 1 / 6 | 7 / 7 | 4 | 3 | 2 | 1 | 1 | 8 | 0 | 27 |
| 2021-05-01 | 107 - 124 | CLEVELAND CAVALIERS v. MIAMI HEAT | * | 38:50 | 25 | 8 / 20 | 4 / 14 | 4 / 6 | 5 / 8 | 1 | 3 | 8 | 2 | 1 | 2 | 3 | 25 |
| 2021-05-04 | 118 - 134 | CLEVELAND CAVALIERS v. PHOENIX SUNS | * | 38:32 | 29 | 11 / 24 | 9 / 19 | 2 / 5 | 5 / 7 | 5 | 2 | 7 | 0 | 0 | 5 | 5 | 33 |
| 2021-05-05 | 105 - 141 | CLEVELAND CAVALIERS v. PORTLAND TRAIL BLAZERS | * | 34:24 | 15 | 6 / 15 | 6 / 12 | 0 / 3 | 3 / 5 | 0 | 0 | 4 | 2 | 0 | 1 | 2 | 11 |
| 2021-05-07 | 110 - 90 | CLEVELAND CAVALIERS @ DALLAS MAVERICKS | * | 36:25 | 27 | 9 / 18 | 9 / 16 | 0 / 2 | 9 / 11 | 2 | 2 | 4 | 0 | 0 | 2 | 3 | 26 |
| 2021-05-09 | 97 - 124 | CLEVELAND CAVALIERS v. DALLAS MAVERICKS | * | 32:17 | 24 | 8 / 19 | 5 / 14 | 3 / 5 | 5 / 7 | 2 | 1 | 7 | 0 | 0 | 2 | 1 | 23 |
| 2021-05-10 | 102 - 111 | CLEVELAND CAVALIERS v. INDIANA PACERS | * | 36:39 | 25 | 7 / 26 | 6 / 20 | 1 / 6 | 10 / 12 | 2 | 3 | 8 | 1 | 0 | 3 | 1 | 21 |
| 2021-05-12 | 102 - 94 | CLEVELAND CAVALIERS v. BOSTON CELTICS | * | 32:13 | 28 | 7 / 15 | 6 / 13 | 1 / 2 | 13 / 16 | 2 | 0 | 8 | 0 | 1 | 5 | 1 | 31 |
| 2021-05-14 | 120 - 105 | CLEVELAND CAVALIERS @ WASHINGTON WIZARDS | * | 30:32 | 26 | 8 / 16 | 6 / 12 | 2 / 4 | 8 / 8 | 1 | 0 | 4 | 0 | 0 | 6 | 3 | 29 |
| 2021-05-16 | 123 - 109 | CLEVELAND CAVALIERS @ BROOKLYN NETS | * | 20:03 | 16 | 5 / 11 | 4 / 7 | 1 / 4 | 5 / 5 | 2 | 0 | 5 | 1 | 0 | 1 | 2 | 19 |