| 2021-09-24 | 63 - 73 | LYONSO BASKET @ AS KAYSERSBERG | * | 31:44 | 22 | 11 / 17 | 11 / 16 | 0 / 1 | 0 / 1 | 4 | 3 | 2 | 4 | 1 | 2 | 3 | 29 |
| 2021-10-01 | 84 - 64 | LYONSO BASKET v. FC MULHOUSE BASKET | * | 28:51 | 6 | 3 / 7 | 3 / 7 | 0 / 0 | 0 / 0 | 3 | 3 | 0 | 1 | 0 | 2 | 3 | 11 |
| 2021-10-08 | 77 - 83 | LYONSO BASKET @ ANDREZIEUX BOUTHEON | * | 26:33 | 11 | 5 / 11 | 5 / 11 | 0 / 0 | 1 / 1 | 5 | 3 | 1 | 0 | 1 | 3 | 4 | 16 |
| 2021-10-12 | 70 - 83 | LYONSO BASKET v. BESANCON BCD | * | 12:46 | 1 | 0 / 3 | 0 / 3 | 0 / 0 | 1 / 2 | 0 | 0 | 0 | 2 | 2 | 0 | 3 | -3 |
| 2021-10-16 | 55 - 68 | LYONSO BASKET @ SO PONT DE CHERUY CHARVIEU | * | 31:21 | 16 | 4 / 8 | 4 / 8 | 0 / 0 | 8 / 10 | 3 | 3 | 2 | 0 | 3 | 1 | 1 | 16 |
| 2021-10-22 | 80 - 67 | LYONSO BASKET v. STB LE HAVRE | * | 30:29 | 9 | 4 / 9 | 4 / 9 | 0 / 0 | 1 / 2 | 2 | 1 | 1 | 0 | 1 | 1 | 2 | 7 |
| 2021-10-26 | 76 - 83 | LYONSO BASKET @ ASGE BASKETBALL | * | 19:44 | 2 | 1 / 4 | 1 / 4 | 0 / 0 | 0 / 0 | 4 | 0 | 0 | 2 | 2 | 0 | 3 | 3 |
| 2021-10-29 | 75 - 68 | LYONSO BASKET v. UNION SPORTIVE AVIGNON | * | 22:46 | 3 | 1 / 1 | 1 / 1 | 0 / 0 | 1 / 2 | 4 | 1 | 0 | 2 | 2 | 0 | 3 | 7 |
| 2021-11-02 | 79 - 71 | LYONSO BASKET @ SOM BOULOGNE | * | 27:55 | 14 | 5 / 9 | 5 / 9 | 0 / 0 | 4 / 4 | 3 | 4 | 0 | 0 | 0 | 4 | 2 | 21 |
| 2021-11-05 | 75 - 81 | LYONSO BASKET v. UNION BASKET CHARTRES METROPOLE | * | 19:34 | 6 | 2 / 5 | 2 / 5 | 0 / 0 | 2 / 2 | 4 | 2 | 0 | 0 | 0 | 0 | 2 | 9 |
| 2021-11-09 | 75 - 62 | LYONSO BASKET @ CAEN BASKET CALVADOS | * | 23:14 | 2 | 1 / 4 | 1 / 4 | 0 / 0 | 0 / 2 | 4 | 0 | 0 | 1 | 1 | 0 | 4 | 1 |
| 2021-11-12 | 65 - 60 | LYONSO BASKET v. BC ORCHIES | * | 27:49 | 14 | 3 / 6 | 3 / 6 | 0 / 0 | 8 / 8 | 3 | 3 | 1 | 1 | 3 | 1 | 3 | 17 |
| 2021-11-19 | 69 - 49 | LYONSO BASKET v. POLE FRANCE BASKETBALL | * | 21:19 | 7 | 3 / 7 | 3 / 7 | 0 / 0 | 1 / 1 | 4 | 3 | 2 | 0 | 1 | 1 | 0 | 12 |
| 2021-12-03 | 76 - 55 | LYONSO BASKET v. AS KAYSERSBERG | * | 18:04 | 7 | 3 / 7 | 3 / 7 | 0 / 0 | 1 / 1 | 3 | 3 | 0 | 1 | 1 | 1 | 4 | 10 |
| 2021-12-10 | 78 - 72 | LYONSO BASKET @ FC MULHOUSE BASKET | * | 18:46 | 4 | 2 / 5 | 2 / 5 | 0 / 0 | 0 / 0 | 3 | 4 | 0 | 0 | 4 | 1 | 4 | 5 |
| 2021-12-17 | 58 - 77 | LYONSO BASKET v. ANDREZIEUX BOUTHEON | * | 33:44 | 14 | 6 / 8 | 6 / 8 | 0 / 0 | 2 / 2 | 2 | 0 | 0 | 2 | 1 | 1 | 3 | 16 |
| 2022-01-14 | 74 - 63 | LYONSO BASKET v. SO PONT DE CHERUY CHARVIEU | * | 15:56 | 4 | 2 / 6 | 2 / 6 | 0 / 0 | 0 / 1 | 4 | 4 | 1 | 0 | 2 | 0 | 5 | 6 |
| 2022-01-21 | 74 - 79 | LYONSO BASKET @ STB LE HAVRE | * | 17:44 | 6 | 1 / 7 | 1 / 7 | 0 / 0 | 4 / 4 | 2 | 2 | 1 | 0 | 3 | 0 | 3 | 2 |
| 2022-01-25 | 92 - 68 | LYONSO BASKET v. ASGE BASKETBALL | | 17:52 | 10 | 4 / 10 | 4 / 9 | 0 / 1 | 2 / 2 | 4 | 2 | 0 | 0 | 2 | 3 | 0 | 11 |
| 2022-01-28 | 75 - 85 | LYONSO BASKET @ UNION SPORTIVE AVIGNON | * | 20:02 | 8 | 4 / 6 | 4 / 6 | 0 / 0 | 0 / 0 | 3 | 1 | 0 | 1 | 1 | 0 | 4 | 10 |
| 2022-02-01 | 82 - 79 | LYONSO BASKET v. SOM BOULOGNE | * | 16:53 | 8 | 4 / 7 | 4 / 7 | 0 / 0 | 0 / 0 | 5 | 1 | 1 | 0 | 2 | 0 | 3 | 10 |
| 2022-02-04 | 82 - 79 | LYONSO BASKET @ UNION BASKET CHARTRES METROPOLE | * | 23:12 | 11 | 2 / 6 | 2 / 6 | 0 / 0 | 7 / 10 | 3 | 4 | 0 | 0 | 5 | 1 | 5 | 7 |
| 2022-02-08 | 81 - 78 | LYONSO BASKET v. CAEN BASKET CALVADOS | * | 31:12 | 17 | 7 / 9 | 7 / 9 | 0 / 0 | 3 / 4 | 9 | 2 | 0 | 1 | 1 | 2 | 2 | 27 |
| 2022-02-11 | 74 - 69 | LYONSO BASKET @ BC ORCHIES | * | 26:39 | 17 | 6 / 11 | 6 / 11 | 0 / 0 | 5 / 8 | 6 | 4 | 1 | 0 | 1 | 2 | 2 | 21 |
| 2022-02-15 | 78 - 86 | LYONSO BASKET @ BESANCON BCD | * | 7:59 | 4 | 2 / 3 | 2 / 3 | 0 / 0 | 0 / 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4 | 4 |
| 2022-02-18 | 71 - 74 | LYONSO BASKET @ POLE FRANCE BASKETBALL | * | 35:00 | 23 | 8 / 11 | 8 / 11 | 0 / 0 | 7 / 11 | 1 | 5 | 1 | 1 | 3 | 2 | 1 | 23 |
| 2022-03-11 | 80 - 58 | LYONSO BASKET @ STADE ROCHELAIS | * | 30:47 | 14 | 4 / 8 | 4 / 8 | 0 / 0 | 6 / 9 | 5 | 0 | 0 | 0 | 4 | 0 | 0 | 8 |
| 2022-03-15 | 53 - 85 | LYONSO BASKET v. ANGERS BC 49 | * | 21:49 | 12 | 3 / 11 | 3 / 11 | 0 / 0 | 6 / 6 | 3 | 3 | 0 | 1 | 1 | 0 | 3 | 10 |
| 2022-03-18 | 95 - 61 | LYONSO BASKET @ CEP LORIENT | * | 14:40 | 0 | 0 / 5 | 0 / 5 | 0 / 0 | 0 / 0 | 3 | 0 | 0 | 0 | 2 | 0 | 2 | -4 |
| 2022-03-22 | 66 - 67 | LYONSO BASKET v. UNION POITIERS BASKET 86 | * | 27:00 | 7 | 3 / 6 | 3 / 6 | 0 / 0 | 1 / 2 | 1 | 2 | 1 | 0 | 3 | 3 | 4 | 7 |
| 2022-03-25 | 85 - 65 | LYONSO BASKET @ RUEIL ATHLETIC CLUB | * | 22:13 | 19 | 8 / 12 | 8 / 12 | 0 / 0 | 3 / 4 | 2 | 2 | 1 | 1 | 3 | 0 | 3 | 17 |
| 2022-04-01 | 75 - 79 | LYONSO BASKET v. STADE ROCHELAIS | * | 22:07 | 20 | 8 / 10 | 8 / 10 | 0 / 0 | 4 / 5 | 3 | 4 | 0 | 0 | 1 | 1 | 3 | 24 |
| 2022-04-05 | 76 - 60 | LYONSO BASKET @ ANGERS BC 49 | * | 20:46 | 6 | 3 / 10 | 3 / 10 | 0 / 0 | 0 / 0 | 6 | 1 | 1 | 2 | 1 | 1 | 1 | 9 |
| 2022-04-15 | 79 - 65 | LYONSO BASKET v. RUEIL ATHLETIC CLUB | | 28:46 | 10 | 4 / 9 | 4 / 9 | 0 / 0 | 2 / 2 | 5 | 5 | 0 | 0 | 4 | 0 | 2 | 11 |
| 2022-04-24 | 81 - 77 | LYONSO BASKET v. CAEN BASKET CALVADOS | * | 30:55 | 14 | 5 / 9 | 5 / 9 | 0 / 0 | 4 / 7 | 1 | 2 | 2 | 0 | 4 | 1 | 3 | 9 |
| 2022-04-29 | 96 - 72 | LYONSO BASKET @ CAEN BASKET CALVADOS | * | 27:17 | 19 | 8 / 15 | 8 / 15 | 0 / 0 | 3 / 5 | 7 | 1 | 0 | 0 | 4 | 2 | 3 | 16 |
| 2022-05-01 | 97 - 63 | LYONSO BASKET @ CAEN BASKET CALVADOS | * | 26:37 | 13 | 5 / 9 | 5 / 9 | 0 / 0 | 3 / 4 | 3 | 2 | 0 | 0 | 3 | 2 | 2 | 12 |
